Protein Alignment Jhe and Ces2b

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001094469.1
• Gene: Ces2b / 679149
• RGDID: 1591847
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 168/551 - (30%)
• Similarity: 248/551 - (45%)
• Gaps: 92/551 - (16%)

  Fly    58 FMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQ----------KNYLLPTPVVYGDED 112
            |:|||:|.||:|.|||:.|:......|:.|.::....|:|          |...|..|.|...||
  Rat    60 FLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAMCLQNLDVINAEGLKEMKLKLPPVSMSED 124

  Fly   113 CLYLNVYRP--EIRKSALPVMVYIHGGGFFGGSA----GPGVTGPEYFMDSGEVILVTMAYRLGP 171
            |||||:|.|  ....|.|||||:|||||...|.|    |..:|..|      ::::||:.||||.
  Rat   125 CLYLNIYAPAHAHEGSNLPVMVWIHGGGLMTGMASMYDGSLLTVNE------DLVVVTIQYRLGV 183

  Fly   172 FGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGL 236
            .||.||.|....||:|..||..||||||:||..|||:|.||||||:||||.....|::||.|.||
  Rat   184 LGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTCVSTHVVSPMSQGL 248

  Fly   237 FHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLK 301
            ||..|..||.|.:|:.||:.....:.::|:   |.....:.:..|...||..:..::|
  Rat   249 FHGAIMESGVALLPYLIADTSEMFSTMVAK---VSGCEAMDSEALVHCLRAKSEAEIL------- 303

  Fly   302 YWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLG--------TVP-GEGAVRVV 357
              .::.:....|.|.:|    .||..||.::||......:|.::|        |:| ..|..:::
  Rat   304 --AINKVVQMVPAVVDG----EFLPRHPKELLASEDFRPVPSIIGVNNDEYGWTIPLVMGTTQMI 362

  Fly   358 NILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLI 422
            ..|..|.|:........:|:..|             :..|||:|.|.....:...|..| |..|:
  Rat   363 KELSRENLQAILKKTTAQLMLPL-------------ECSDLLMEEYMGDIEDPKTLQAQ-FTELM 413

  Fly   423 SDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSP 487
            .|..|..|.....|....|.  |||.|.|.:|  :::.......:|...:|    |::.::|  .
  Rat   414 EDFMFVIPALQVAHFQCSHA--PVYFYEFQHQ--ITFLKDIRPPHVKADHG----DEIPFVF--G 468

  Fly   488 LLFPDFQRNSTEAKVIHS--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAP 550
            ..|.|.:.:.||.:.:.|  .:.|:.:||:.|.| |||.|:                |....:..
  Rat   469 YFFWDMKTDFTEEEKLLSRRMMKYWANFARHGNP-NSEGLS----------------YWPVMDHD 516

  Fly   551 DAYQGFEVH--VASEFQTDRVNLWSHILNEK 579
            ..|...:..  |....:..|:..|:..|.:|
  Rat   517 QQYLQLDTQPAVGRALKARRLQFWTKTLPQK 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	161/495 (33%)
Ces2b	NP_001094469.1	COesterase	32..540	CDD:395084	165/542 (30%)