DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jhe and tg

DIOPT Version :9

Sequence 1:	NP_001163166.1	Gene:	Jhe / 36780	FlyBaseID:	FBgn0010052	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001316794.1	Gene:	tg / 567631	ZFINID:	ZDB-GENE-030519-1	Length:	2733	Species:	Danio rerio

Alignment Length:	517	Identity:	153/517 - (29%)
Similarity:	222/517 - (42%)	Gaps:	84/517 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TVCPPSVGCLKGTN----LQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKM 93
            :|..|..|.|.|.:    :.|..|:|...|:|:|||.|||||||||.|: .....|.::|:..:.
Zfish  2165 SVSIPDHGTLLGESEVKPITGSDSKRVTYFLGVPYARPPIGDLRFSPPQ-PADWTGTWNATFFRS 2228

  Fly    94 DCIQKNYLLPTPVVYGDEDCLYLNVY-RPEIRKSALPVMVYIHGGG--FFGGSAGPGVTGPEYFM 155
            .|:|...|..:.   ..||||||||: ...:.|:| ||:|:.|..|  ...||         |..
Zfish  2229 SCLQPGDLTDSS---SSEDCLYLNVFVASSVAKNA-PVLVFFHNSGSDLLDGS---------YLA 2280

  Fly   156 DSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAG 220
            ..|.:|:||.::|:..|||||...:.:.||:||:||..||.|||:||..|||||.:||:..:..|
Zfish  2281 AVGNIIVVTASFRMAAFGFLSAGSSALPGNYGLQDQAAALGWVQKNIALFGGDPTKVTVGAERNG 2345

  Fly   221 GVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARL--LAEFAD--VPDARNLSTVKL 281
            ...|.:||.||.:..||.|.:.|.|:...|..:......||:.  ||...|  ..|...|.....
Zfish  2346 ADIASLHLTSPSASSLFSRALLMGGSVFSPAVVMSSSKAQAQTSSLARELDCQAADPSQLLDCLR 2410

  Fly   282 TKALRRINA--TKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLL 344
            :|....|||  ||||.....|:.|.        |||:..:     :...|...|..|......:|
Zfish  2411 SKPAHSINAAQTKLLAVSGPLQAWS--------PVVDGNV-----VREMPSVALQSGRFHKAEIL 2462

  Fly   345 LGTVPGEGAV-RVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQH 408
            ||:...:|.: |..||...|.|:.    |.|...........|...|.....:......::..||
Zfish  2463 LGSSFEDGLISRAKNIKNFEQLQG----RADSKTAFYAALSNSLGGDDANAFVKEAATWFYSLQH 2523

  Fly   409 EVNELTVQGFMNLISDRGFKQPLYNTIHK--NVCHTPNPVYLYSFN-----YQGPLSYASAYTSA 466
            ..   |..|: |:     |.:.|.|....  .:|.|.:....::.|     |...|...:||.|.
Zfish  2524 SP---TPSGY-NV-----FSRALENATRDLFIICPTVDMAEFWAANTQTGVYMYHLPENAAYNSV 2579

  Fly   467 NVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSF---------VDYFVHFAKFGKP 519
            :::...      |:.|||..||        :.|.:.:.|:         ::|..:|.|.|.|
Zfish  2580 DLSVPM------DVQYLFGVPL--------AAEQRDLFSYKEKTFTLQIMNYMANFIKSGNP 2627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	151/510 (30%)
tg	NP_001316794.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575591
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930