DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jhe and si:dkey-30c15.17

DIOPT Version :9

Sequence 1:	NP_001163166.1	Gene:	Jhe / 36780	FlyBaseID:	FBgn0010052	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_003200472.2	Gene:	si:dkey-30c15.17 / 561375	ZFINID:	ZDB-GENE-060503-450	Length:	657	Species:	Danio rerio

Alignment Length:	564	Identity:	164/564 - (29%)
Similarity:	248/564 - (43%)	Gaps:	106/564 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 PSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQK--- 98
            |.|..|.| .::|...|:...|.|||||.||:||.|::.|..:...|..|:|:.|:..|:|.
Zfish   136 PVVVTLLG-RVRGLTLEKAHVFYGIPYADPPVGDKRWAPPSPVSPWLYTYNATFPRPACMQMCAG 199

  Fly    99 --NYLLPTPVVYGDEDCLYLNVYRPEI------RKSALPVMVYIHGGGFFGGSAGPGVTGPEYFM 155
              :.|.|..|   .||||||||:.|..      :.:||||||:||||.|..|||...:....|..
Zfish   200 EFSRLCPPEV---SEDCLYLNVFVPVSVNLSLPKVTALPVMVWIHGGDFIAGSASKPLYDGRYIS 261

  Fly   156 DSGEVILVTMAYRLGPFGFLST-QDAVMS--GNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQ 217
            :....::|.|.||||.||||.| :|...|  ||:|:.||..||.|||.||..|||||.:||:||:
Zfish   262 NYSNTVVVNMEYRLGAFGFLVTGKDPESSAVGNYGILDQQAALHWVQENIAAFGGDPNKVTLFGE 326

  Fly   218 SAGGVAAHMHLLSPRSHGLF-HRVISMSGTANVPFAIAEQPL----EQARLLAEFA--------D 269
            |||..:..:||:...|..|| |..|.     ::||::   ||    :..:|..:||        |
Zfish   327 SAGAQSVSLHLMMQSSETLFRHAAIQ-----SLPFSL---PLKTRWDAMKLGWDFAKLTNCSVFD 383

  Fly   270 VPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLA 334
            :|..|:||:..:..|..: :.:|::|....|:.::     .:.|.::..|     |...|:....
Zfish   384 LPCMRSLSSEDVLNAQIK-SGSKIINPFRFLEVFE-----TWGPFIDGQL-----LKEQPITAFQ 437

  Fly   335 QGMPTSI-PLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDL 398
            :|...|. |::|||...||.:.|.         ::||.....|  |.:.:.|:..:....|::..
Zfish   438 KGHWQSYKPVILGTTSEEGVMFVY---------RNFNKSVSML--ECVLYTAAIFKQHALKILHK 491

  Fly   399 LVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNY--QGPLSYAS 461
            .:..|......|.      ...:::|..|..|...:....| .....|::|.|::  ..|..:|.
Zfish   492 YIPFYRNQDRRVM------LSQMVTDYVFSCPARQSARSGV-KVGGAVWMYVFDHAPSDPNIWAE 549

  Fly   462 AYTSANVTGKYGVVHCDDLLYLFRSPLLFP--DFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSES 524
            .....|.:     .|..:|.:||.|.   |  :|.....|..:.:....|:..||..|.|.:.:.
Zfish   550 LTFCYNHS-----CHGAELPFLFDSA---PSTNFTFTPQERLLANRMACYWGMFAHTGDPNSRDE 606

  Fly   525 LTPCSIE--------------------VLQSRP-----DGICDY 543
            .|....|                    .|||.|     |..||:
Zfish   607 QTHFCREQRLPVWPRYTDIGGWTILNLTLQSHPQHGSRDHFCDF 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	153/518 (30%)
si:dkey-30c15.17	XP_003200472.2	COesterase	134..651	CDD:306613	164/564 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840