Protein Alignment Jhe and Nlg1

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 592
• Identity: 157/592 - (26%)
• Similarity: 239/592 - (40%)
• Gaps: 124/592 - (20%)

  Fly    56 EAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYG----------- 109
            :.|:|:|||..|.|:.||..|.......|:..|......|.||   ||....:|
  Fly   182 DQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQK---LPDLSPHGSENMSRARHKH 243

  Fly   110 -----------DEDCLYLNVYRPEIRKSALP----VMVYIHGGGFFGGSAGP--GVTGPEYFMDS 157
                       .|||||||:|.|.....:.|    |:||:||..|...|..|  |.....|
  Fly   244 LSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSY---- 304

  Fly   158 GEVILVTMAYRLGPFGFLSTQ-DAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGG 221
            ||||:||:.||||..|||... ||....|:.|.||..||.|::.||..||||..|||:.|.|.|.
  Fly   305 GEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGA 369

  Fly   222 VAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALR 286
            ...:..::||.:.|||||.|.|||:|...:|.:.|.|:....:|...:.|         |.:.:.
  Fly   370 ACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECP---------LNEHVE 425

  Fly   287 RINATKLLNAGDGLKYWDVDHM--------TNFRPVVE------EGLEVDAFLNAHPMDMLAQGM 337
            ..:...||:.....:|.|:.|:        |:..|:|:      :..:|......|
  Fly   426 AEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEH--------- 481

  Fly   338 PTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEV 402
            .:...||.|....|....:..:...|.||:  |.|     ..||.|   :.|.|.:...||.:..
  Fly   482 FSRYDLLFGITESESYHTLAALALEEGLRE--NER-----DNLLRF---YMQSRFDIRPDLALAA 536

  Fly   403 YFQGQHEVNELTVQG--------FMNLISDRGFKQPLYNT--IHKNVCHTPNPVYLYSFN-YQGP 456
            ..:...::....::.        .::::||.....||..|  .|.:| :..|.:|::..| ..||
  Fly   537 TLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADV-NRRNYMYVFGHNSATGP 600

  Fly   457 LSYASAYTSANVTGKYGVVHCDDLLYLFRSPLL----FPDFQRNSTEAKVIHSFVDYFVHFAKFG 517
            .    |:...::.|       ::|.::|.:||.    ||.......|..:..:.:.|:.:|.|.|
  Fly   601 F----AHLPHSIMG-------EELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTG 654

  Fly   518 KPR--------NSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQ--GFEVHVASEFQTDRVNLW 572
            .|:        ||.:|.       ..|.|  .|:.||.....||.  |....|..:::...:|.|
  Fly   655 NPKAPWKGIFINSHALE-------WDRYD--LDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFW 710

  Fly   573 SHILNEK 579
            :..|.::
  Fly   711 NKELPDE 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	145/536 (27%)
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	155/583 (27%)