Protein Alignment Jhe and alpha-Est8

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 171/565 - (30%)
• Similarity: 259/565 - (45%)
• Gaps: 58/565 - (10%)

  Fly    40 GCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPT 104
            |.:||...|......:.:|.|||:|.||:|:|||..|........:...:..:....|.|.:|..
  Fly    40 GKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQVNIVLKQ 104

  Fly   105 PVVYGDEDCLYLNVYRPEIR-KSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYR 168
              |.|.|||||||||..|:. ...|||:|:|:||||..|.|...:..|:|.| ...|:||.::||
  Fly   105 --VQGSEDCLYLNVYTRELHPHRPLPVLVWIYGGGFQMGEASRDLYSPDYIM-MEHVVLVVISYR 166

  Fly   169 LGPFGFLSTQDAVMS--GNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSP 231
            ||..||||..|..:.  ||.|||||.:|||||:||.:||||||..:|:||:||||.:.|..:|:.
  Fly   167 LGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMMLTD 231

  Fly   232 RSHGLFHRVISMSGTANVPFAIA----EQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATK 292
            ::.||||:.|.|||:|..|:|..    ..|...|:......|..|.      .:...|::..|:.
  Fly   232 QAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDR------DIFAHLKKCKASS 290

  Fly   293 LLNAGDGLKYWDVDH----MTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGA 353
            :|...:.:...:..|    |.:|.|.:|..|.....:...|::|:......|||:::|....||.
  Fly   291 MLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGL 355

  Fly   354 VRV--VNILGNETLRQSFNLRFDELL------QELLEFPASFSQDRREKMMDLLVEVYFQGQHEV 410
            :..  ||             ::.|||      :.|....|...:.:|:.....:.|:|| |....
  Fly   356 LMFPEVN-------------KWPELLCQLGDCENLAPQDAHVDEQQRKAFGKKVRELYF-GDRTP 406

  Fly   411 NELTVQGFMNLISDRGFKQPLYNTIHKNVCHTP-NPVYLYSFNYQGP-LSYASAYTSANVTGKYG 473
            ...|:..:.:|.|.:.|...::.|:.....|.| .|.:||.|::... .:.....|.....  .|
  Fly   407 GRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKV--RG 469

  Fly   474 VVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPD 538
            ..|.|||.|||.:... ...:|.:.|.|.|...|...||||..|.|.     .|...:..:.:|.
  Fly   470 TCHADDLSYLFYNAAA-KKLKRRTAEFKTIKRLVSMVVHFAISGDPN-----IPMVCQDEKEQPR 528

  Fly   539 GICDYHEFANAPDAYQ----GFEVHVASEFQTDRVNLWSHILNEK 579
            |.  :...:.....:|    ..:|||....:.:::.||..|.:.:
  Fly   529 GA--WLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLWDCIYDRE 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	161/507 (32%)
alpha-Est8	NP_524259.2	COesterase	34..564	CDD:395084	168/556 (30%)