Protein Alignment Jhe and Est-6

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 166/563 - (29%)
• Similarity: 259/563 - (46%)
• Gaps: 48/563 - (8%)

  Fly     9 LLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRF 73
            :::|..|..|..    |..|.|.|.|..|. |.|:|.:...|.|     :..||||.||.|||||
  Fly     9 IIVLSCLWLGSN----ASDTDDPLLVQLPQ-GKLRGRDNGSYYS-----YESIPYAEPPTGDLRF 63

  Fly    74 SNPK-VMPKLLGMYDASAPKMDCIQKNYLLP-TPVVYGDEDCLYLNVYRPE-IRKSALPVMVYIH 135
            ..|: ...|...::||:...:.|:|.:...| ...:.|:||||.::||:|: .::::.||:.:||
  Fly    64 EAPEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIH 128

  Fly   136 GGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQR 200
            ||.|..|:|..  .|.|..|..|:.|||.::|||||.||:||.|..:.||:|||||.|||:|:::
  Fly   129 GGAFMFGAAWQ--NGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQ 191

  Fly   201 NIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLA 265
            ||..|||:||.|.:.|.||||.:.|:.:|......|.....|.||.|..|:.|.:....:|..|.
  Fly   192 NIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELG 256

  Fly   266 EFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPM 330
            .......|.:.:::|  |.|:...|::|:.|......:.......|.||:|.....||.:...|.
  Fly   257 RNVGCESAEDSTSLK--KCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPR 319

  Fly   331 DMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQS------FNLRFDELLQELLEFPASFSQ 389
            |::..|....:|..:..|..:|......:|..   |:|      .|.|:.||...||     |.:
  Fly   320 DVIKSGKFGQVPWAVSYVTEDGGYNAALLLKE---RKSGIVIDDLNERWLELAPYLL-----FYR 376

  Fly   390 D-RREKMMD---LLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYS 450
            | :.:|.||   ..::..:.|....:..:......|.:|..||.....::..:..:..:|.|.|.
  Fly   377 DTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYV 441

  Fly   451 FNYQGPLSYASAYTSANVTG-KYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFA 514
              |..|.....|...||.|. .:|.||.||...:|.:  ...|.:....|..:..:|::....||
  Fly   442 --YDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFEN--FVRDVEMRPDEQIISRNFINMLADFA 502

  Fly   515 -------KFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAP 550
                   |:|:....:::.....::|....|| |...:....|
  Fly   503 SSDNGSLKYGECDFKDNVGSEKFQLLAIYIDG-CQNRQHVEFP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	152/509 (30%)
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	158/530 (30%)