Protein Alignment Jhe and Ces1b

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 610
• Identity: 167/610 - (27%)
• Similarity: 261/610 - (42%)
• Gaps: 134/610 - (21%)

  Fly    32 LTVCP--------PSVGCLKGTNLQGYQS-ERFE----AFMGIPYALPPIGDLRFSNPKVMPKLL 83
            |.:||        |.|...:|..|..|.| |.||    .|:|:|:|.||:|.|||:.|:......
Mouse    11 LALCPIWGHSPSSPVVDTTQGKILGKYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWS 75

  Fly    84 GMYDASAPKMDCIQK-------NYLLPT-----PVVYGDEDCLYLNVYRP-EIRKSA-LPVMVYI 134
            .:.:|::....|.|.       :.:|.|     |.:: .|||||||:|.| ::.||: |||||:|
Mouse    76 FVKNATSYPPMCSQDAVAVQLLSDMLSTKKESIPPLF-SEDCLYLNIYSPADLTKSSLLPVMVWI 139

  Fly   135 HGGGFFGGSA----GPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLAL 195
            ||||...|.|    |..::..|      .|::||:.||||.:|..||.|....||:...||..||
Mouse   140 HGGGLMTGGASLYNGLALSAHE------NVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAAL 198

  Fly   196 RWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTA--NVPFAIAEQPL 258
            ||||.||..|||:|..||:||.|||||:..:.:|||.:..||||.||.|...  |:...:   .|
Mouse   199 RWVQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITL---DL 260

  Fly   259 EQARLLAEFADVPDARNLSTVKLTKALR------------RINATKLLNAGDGLKYWDVDHMTNF 311
            ....|....|.|....:.|:..:.:.||            ::..||:..|....|    |: |:.
Mouse   261 VACDLSQMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKK----DN-TSM 320

  Fly   312 RPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILG--------NETLRQS 368
            ..|::     ...|...|.::||:...:::|.::|....|....:..:||        ||.....
Mouse   321 STVID-----GVVLPKAPEEILAEKSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEGKMNEETASL 380

  Fly   369 FNLRF-------DELLQELLEFPASFSQD---RREKMMDLLVEVYFQGQHEVNELTVQGFMNLIS 423
            ...||       :.|:..::|.....:.|   :|:.::|:..:|:|            |...::.
Mouse   381 LLRRFHSDLNISESLIPAVIEKYLRGTDDPAKKRDLLLDMFSDVFF------------GIPAVLL 433

  Fly   424 DRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPL 488
            .|..:....:|            |:|.|.|:.  |:.|......|.|.:|    |::..:|..||
Mouse   434 SRSLRDAGVST------------YMYEFRYRP--SFVSDKRPQTVEGDHG----DEIFSVFGIPL 480

  Fly   489 LFPDFQRNSTE-AKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDA 552
            |........|. :|::..|   :.:||:.|.|..                :|:..:.|:......
Mouse   481 LKEGTSEEETNLSKMVMKF---WANFARNGNPNG----------------EGLPHWPEYDEKEGY 526

  Fly   553 YQ-GFEVHVASEFQTDRVNLWSHIL 576
            .| |.....|...:.:.|..|:.:|
Mouse   527 LQIGATTQQAQRLKAEEVAFWTELL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	155/544 (28%)
Ces1b	NP_001074841.1	COesterase	22..547	CDD:395084	162/593 (27%)