DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jhe and CG9287

DIOPT Version :9

Sequence 1:	NP_001163166.1	Gene:	Jhe / 36780	FlyBaseID:	FBgn0010052	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	540	Identity:	161/540 - (29%)
Similarity:	238/540 - (44%)	Gaps:	106/540 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 PSVGCLKGTNLQ-GYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDC---IQ 97
            |::|.::|..|: .:.......|:.:.||.||.|..||..|:.:.....:.||:|.|:.|   :.
  Fly    39 PTLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVS 103

  Fly    98 KNYLLPTPVVYGDEDCLYLNVYRPEIRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVIL 162
            .:.|.....|...||||.:.:..|.: .|.|||:|||||...:.||...  ..|:|.::. :|:|
  Fly   104 MDSLRRLDDVLDVEDCLTMTITTPNV-TSRLPVLVYIHGEYLYEGSNSE--APPDYLLEK-DVVL 164

  Fly   163 VTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMH 227
            ||..|||||||||||:...:.||.|..|..|||::|:..|::|||||.|||:.||..|...||:.
  Fly   165 VTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLL 229

  Fly   228 LLSP-RSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVK-LTKALRRINA 290
            .||| ...||||:||..||:|.:|..:.|.|.:.|:.:|:.||.    .:.||: |...|..:.|
  Fly   230 TLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADC----KMVTVRDLNTCLMELTA 290

  Fly   291 TKLLNAGDGLKYWDVDHMTNFRPVVEEGLE------------------VDAFLNAHPMDMLAQGM 337
            .:||.|                 .:|..||                  ....|..||.|::.: .
  Fly   291 LELLTA-----------------FMEHALEKSDLGIGHTGGIQFTIGGPSGVLPKHPYDLMLE-T 337

  Fly   338 PTSIPLLLGTVPGEGAVRVVN-ILGNE------------------TLRQSFNLRFDELLQELL-- 381
            ..|.| .:|..|.....||:| |:.|:                  .:||:.......||...:
  Fly   338 NFSYP-AMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYIDHVIRQTVGTDKTMLLTSFVTH 401

  Fly   382 EFPASFSQDRREK-MMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNP 445
            :|   |:::..|. ..|.|:.         ..:.|.|.:|      .|.|:...::.|..|.|:.
  Fly   402 DF---FNRNLMENGTFDTLIP---------RLIDVAGTLN------HKLPVLLALNMNNKHNPDN 448

  Fly   446 VYLYSFNYQGPLS-YASAYTSANVTG--KYGVVHCDDLLYLFRSP-----LLFPDFQRNSTEAKV 502
            .:||||:|.|..: |.......|:..  |.||...|:.||||..|     |..||       ..:
  Fly   449 TFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEALYLFPYPEHVTRLSRPD-------QSM 506

  Fly   503 IHSFVDYFVHFAKFGKPRNS 522
            .|..|:.:.:|...|.|..|
  Fly   507 AHRMVELWTNFVISGNPLGS 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	160/537 (30%)
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	161/540 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440413
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	1	0.950	-	0	Normalized mean entropy	S7868
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750