Protein Alignment Jhe and Aadacl2

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001178635.1
• Gene: Aadacl2 / 295076
• RGDID: 1563197
• Length: 401
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 95/523 - (18%)
• Similarity: 167/523 - (31%)
• Gaps: 220/523 - (42%)

  Fly    25 ALATVDQLT-VCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDA 88
            |:|....|| :|..::|.:           |:|.|:.:...|                     |.
  Rat    38 AVAKTFSLTALCLENIGVM-----------RYEEFISMIINL---------------------DY 70

  Fly    89 SAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPEIRKSALP--VMVYIHGGGFFGGSAGPGVTGP 151
            :.|..|    .::..|...:.|   :.:.:|.|: .||..|  .::|.|||||..||
  Rat    71 TQPHSD----EHITVTDTAFVD---IPVRLYLPK-SKSEAPRRAVIYFHGGGFCFGS-------- 119

  Fly   152 EYFMDSG------------EVILVTMAYRLGPFGFLSTQ--DAVMSGNFGLKDQNLALRWVQRNI 202
              |....            :.::|.:.|||.|......|  |.|.:..|.|:|:.|..
  Rat   120 --FKQRAFDFLNRWTASKLDAVVVGVDYRLAPQHHFPAQFEDGVTAVKFFLQDKMLTK------- 175

  Fly   203 RFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEF 267
              :|.||.|:.|.|.|:||..|                          .|:.:|
  Rat   176 --YGVDPTRIAISGDSSGGTLA--------------------------AAVTQQ----------- 201

  Fly   268 ADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDM 332
                       |::..                    :|.|....:.::..||:|   ::.|
  Rat   202 -----------VQIDP--------------------EVKHKFKLQALLYPGLQV---IDTH---- 228

  Fly   333 LAQGMPTSIPLLLGTV-PGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMM 396
                :|:.:....|.| ..:.|:::|::...:          ||.||..:         |:.:.|
  Rat   229 ----LPSHLENERGIVLTRDIAIKLVSLFFTK----------DEALQWAM---------RKNQHM 270

  Fly   397 DLLVEVYFQGQHEVNELTVQGFMN---LISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLS 458
            .|..:..|:            |:|   |:.|:         ..||..:|...:...:|:....:.
  Rat   271 PLESKHLFR------------FVNWSALLPDK---------FRKNYVYTEPVLGRSAFSLPALMD 314

  Fly   459 YASAYTSAN------------VTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFV 511
            :.:....||            :|.:|.|:..|.::|..|         ..|...:|.|..|:..:
  Rat   315 HRALPLLANDAHLQHLPQTYILTCQYDVLRDDGIMYASR---------LQSVGVEVYHDHVEDGI 370

  Fly   512 HFA 514
            |.|
  Rat   371 HGA 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	90/509 (18%)
Aadacl2	NP_001178635.1	Abhydrolase_3	107..372	CDD:400284	73/411 (18%)