Protein Alignment Jhe and Ces1c

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_006255234.2
• Gene: Ces1c / 24346
• RGDID: 2571
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 165/592 - (27%)
• Similarity: 253/592 - (42%)
• Gaps: 129/592 - (21%)

  Fly    36 PPSVGCLKG------TNLQGYQSERFEAFMGIPYALPPIGDLRFSNPK-VMPKLLGMYDASAPKM 93
            ||.|...||      .:|:|: ::....|:|:|:|.||:|.|||:.|: ..|........:.|.|
  Rat    25 PPVVDTTKGKVLGKYVSLEGF-TQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNTTTYPPM 88

  Fly    94 DCIQKNY-------LLPT-----PVVYGDEDCLYLNVYRPE--IRKSALPVMVYIHGGGFFGGSA 144
             |.|...       :|.|     |:.: .|||||||:|.|.  .:.|.|||||:|||||...|.|
  Rat    89 -CSQDGVVGKLLADMLSTGKENIPLEF-SEDCLYLNIYSPADLTKNSRLPVMVWIHGGGLIIGGA 151

  Fly   145 GP----GVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFF 205
            .|    .::..|      .|::||:.||||.:|..||.|....||:...||..||||||.||..|
  Rat   152 SPYSGLALSAHE------NVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANF 210

  Fly   206 GGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSG---TANV----PFAIAEQPLEQARL 263
            ||:|..|||||:|||||:..:.:|||.:..||||.||.||   |.|:    ..|:|:.
  Rat   211 GGNPDSVTIFGESAGGVSVSVLVLSPLAKNLFHRAISESGVVLTTNLDKKNTQAVAQM------- 268

  Fly   264 LAEFADVPDARNLSTVKLTKALR------------RINATKLLNAGDGLKYWDVDHMTNFRPVVE 316
               .|.:....|.|:..:.:.||            :::.|.:....||:          ..|...
  Rat   269 ---IATLSGCNNTSSAAMVQCLRQKTEAELLELTVKLDNTSMSTVIDGV----------VLPKTP 320

  Fly   317 EGLEVDAFLNAHP--MDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQE 379
            |.:..:...|..|  :....|.....||.::|.:..||.:       ||.:..|...||...|
  Rat   321 EEILTEKSFNTVPYIVGFNKQEFGWIIPTMMGNLLSEGRM-------NEKMASSLLRRFSPNL-- 376

  Fly   380 LLEFPASFSQDRREKMMDLLVEVYFQGQHE---VNELTVQGFMNLISDRGFKQPLYNTIHKNVCH 441
                      :..|.::..::|.|.:|..:   ..||    .:::.||..|..|.. .:.:::..
  Rat   377 ----------NISESVIPAIIEKYLRGTDDPAKKKEL----LLDMFSDVFFGIPAV-LMSRSLRD 426

  Fly   442 TPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTE-AKVIHS 505
            ...|.|:|.|.|:.  |:.|......|.|.:|    |::..:|.:|.|........|. :|::..
  Rat   427 AGAPTYMYEFQYRP--SFVSDQRPQTVQGDHG----DEIFSVFGTPFLKEGASEEETNLSKLVMK 485

  Fly   506 FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQ-GFEVHVASEFQTDRV 569
            |   :.:||:.|.|..                :|:..:.|:.......| |.....|.:.:.:.|
  Rat   486 F---WANFARNGNPNG----------------EGLPHWPEYDQKEGYLQIGATTQQAQKLKGEEV 531

  Fly   570 NLWSHIL 576
            ..|:.:|
  Rat   532 AFWTELL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	155/538 (29%)
Ces1c	XP_006255234.2	COesterase	24..534	CDD:395084	163/586 (28%)