Protein Alignment Jhe and Ces2b

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 602
• Identity: 171/602 - (28%)
• Similarity: 264/602 - (43%)
• Gaps: 108/602 - (17%)

  Fly     9 LLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSER-FEAFMGIPYALPPIGDLR 72
            |||||.:.....|..:.:...        ..|.::|:.:....::. ...|:|||:|.||:|.||
Mouse    18 LLLLGHVQGQDSPEASPIRNT--------HTGQVRGSLVHVKDTKAGVHTFLGIPFAKPPVGPLR 74

  Fly    73 FSNPKVMPKLLGMYDASAPKMDCIQ-----KNYLLPTPVVYGDEDCLYLNVYRP--EIRKSALPV 130
            |:.|:......|:.|.:|....|:|     |...|..|.|...|||||||:|.|  ....|.|||
Mouse    75 FAPPEAPEPWSGVRDGTAHPAMCLQNLGVMKEIKLKLPPVSTSEDCLYLNIYTPAHAHEGSNLPV 139

  Fly   131 MVYIHGGGFFGGSAGPGVTGPEYFMDSG-------EVILVTMAYRLGPFGFLSTQDAVMSGNFGL 188
            ||:|||||...|.|.         |..|       ::::||:.||||..||.||.|....||:|.
Mouse   140 MVWIHGGGLVAGMAS---------MYDGSLLAAIEDLVVVTIQYRLGVLGFFSTGDQHARGNWGF 195

  Fly   189 KDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAI 253
            .||..||||:|:||..|||.|.||||||:||||.:...|::||.|.||||..|..||.|.:|:.|
Mouse   196 LDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSVSSHVVSPMSKGLFHGAIMESGVALLPYLI 260

  Fly   254 AEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEG 318
            .:   ....:....|.:.....:.:..|.:.||..:..::|         .::.:....|.|.:|
Mouse   261 TD---TSEMVSTTVAKLSGCEAMDSEALVRCLRGKSEAEIL---------AINKLVQMIPAVVDG 313

  Fly   319 LEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGN-ETLRQSFNLRFDELLQELLE 382
                .|...||.::||......:|.::|....|....:..::|: :|::        |:.:|.|:
Mouse   314 ----EFFPRHPKELLASEDFHPVPSIIGVNNDEFGWTIPVVMGSAQTIK--------EITRENLQ 366

  Fly   383 FPASFSQDRREKMM-----DLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHT 442
              |.......:.|:     |||:|.|.....:...|.:| |..::.|..|..|.....:....|.
Mouse   367 --AVLKNTTAQLMLPPECSDLLMEEYMGDTEDAQTLQIQ-FTEMMEDFMFVIPALQVAYFQRSHA 428

  Fly   443 PNPVYLYSFNYQGPLSYAS------AYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAK 501
              .||.|.|.:|    .||      .:..|:        |.|::.::|  ...|.|.:.:.||.:
Mouse   429 --SVYFYEFQHQ----IASLKDVRPTHVKAD--------HADEIPFVF--GYFFWDMKLDFTEGE 477

  Fly   502 VIHS--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVH--VAS 562
            .:.|  .:.|:.:||:.|.| |||.|                .|....:..:.|...:..  |..
Mouse   478 KLLSRRMMKYWANFARHGNP-NSEGL----------------PYWPVMDHDEQYLQLDTQPAVGR 525

  Fly   563 EFQTDRVNLWSHILNEK 579
            ..::.|:..|:..|::|
Mouse   526 ALKSRRLQFWTKTLSQK 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	158/517 (31%)
Ces2b	NP_937814.1	COesterase	32..535	CDD:395084	162/579 (28%)