Protein Alignment Jhe and Ces1f

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_659179.1
• Gene: Ces1f / 234564
• MGIID: 2142687
• Length: 561
• Species: Mus musculus
• Alignment Length: 622
• Identity: 174/622 - (27%)
• Similarity: 277/622 - (44%)
• Gaps: 140/622 - (22%)

  Fly    22 FCAALATVDQLTVC-----PPSVGCLKG------TNLQGYQSERFEAFMGIPYALPPIGDLRFSN 75
            |..:|||   ..:|     ||.|....|      .|::|: |:....|:|||:|.||:|.|||:.
Mouse     7 FLVSLAT---CVICGNPSSPPVVDTAHGKVLGKHVNVEGF-SQPVAVFLGIPFAKPPLGSLRFAP 67

  Fly    76 PKVMPKLLGMYDASAPKMDCIQK-------NYLLPTPV----VYGDEDCLYLNVYRPE--IRKSA 127
            |:.......:.:|:.....|.|.       |.|:....    :...|||||||:|.|.  .:.|.
Mouse    68 PQPAEPWSSVKNATTYPPMCSQDAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYTPADFSKNSR 132

  Fly   128 LPVMVYIHGGGF-FGGSA---GPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGL 188
            |||||:|||||. .||::   |..::..|      .|::|.:.|||..:||.||.|....||:|.
Mouse   133 LPVMVWIHGGGLKLGGASSFDGRALSAYE------NVVVVAIQYRLSIWGFFSTGDEHSRGNWGH 191

  Fly   189 KDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVP--F 251
            .||..||.|||.||..|||||..|||||:||||.:..:.:|||.|..||||.||.||.|.:|  |
Mouse   192 LDQVAALHWVQDNIANFGGDPGSVTIFGESAGGYSVSILILSPLSKNLFHRAISESGVAFIPGMF 256

  Fly   252 AIAEQPL-EQARLLAEFADVPDA------RNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMT 309
            ....:|: ||..:.|.......|      |..:..:|.:.:.::|..||...|      |..:..
Mouse   257 TKDVRPITEQIAVTAGCKTTTSAVIVHCMRQKTEEELLEIMHKLNLYKLSLQG------DTKNSD 315

  Fly   310 NFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFD 374
            .|...|.:|:    .|...|.::||:....::|.::|          :|       :|....
Mouse   316 QFVTSVLDGV----VLPKDPKEILAEKNFNTVPYIVG----------IN-------KQECGW--- 356

  Fly   375 ELLQELLEF-PASFSQDRR----------------EKMMDLLVEVYFQGQHEVNELTVQGFMNLI 422
             ||..:..| ||....|::                |.::.:.||.|.:|..:.:::. :|.::.:
Mouse   357 -LLPTMTGFLPADVKLDKKKAIALLEQFASMTGIPEDIIPVAVEKYTKGSDDPDQIR-EGVLDAM 419

  Fly   423 SDRGFKQP--LYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFR 485
            .|..|..|  :.:..|::   |..|.|:|.:.|..  |::|.....||.|.    |.||:..:|.
Mouse   420 GDVAFGVPSVIVSRGHRD---TGAPTYMYEYQYYP--SFSSPQRPKNVVGD----HADDVYSVFG 475

  Fly   486 SPLLFPDFQRNSTEAKVIHS--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFAN 548
            :|:|    :..::|.::..|  .:.::.:||:.|.|...                |:..:.::
Mouse   476 APIL----REGASEEEINLSKMVMKFWANFARNGNPNGK----------------GLPHWPKY-- 518

  Fly   549 APDAYQGFEVHV------ASEFQTDRVNLWSHILNEK 579
              |..:|: :|:      |...:.:.|..|:..|.:|
Mouse   519 --DQKEGY-LHIGGTTQQAQRLKEEEVTFWTQSLAKK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	157/539 (29%)
Ces1f	NP_659179.1	COesterase	24..545	CDD:278561	165/593 (28%)
		Aes	<121..>225	CDD:223730	52/109 (48%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832829
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850