Protein Alignment Jhe and cest-28

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 536
• Identity: 148/536 - (27%)
• Similarity: 223/536 - (41%)
• Gaps: 111/536 - (20%)

  Fly    35 CPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNP-------------KVMPKLLGMY 86
            |.|..|     |:.....:..:.::|||:|.|.:   ||..|             |..|:.
 Worm    21 CGPIQG-----NVYRIGDKTVDGYLGIPFAKPLV---RFKKPEPAGTWEEVRDCTKYGPRC---- 73

  Fly    87 DASAPKMDCI--QKNYLLPTPVVYGDE-DCLYLNVYRPEIRKS-----ALPVMVYIHGGGFFGGS 143
            ..|.|..:.|  ||:.:       .|| :||.|||: .:|..|     ..||||||||||:...:
 Worm    74 PQSGPFAEAINFQKDDI-------PDEANCLTLNVF-SKISDSKNFNKTRPVMVYIHGGGYECSA 130

  Fly   144 AGP----GVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRF 204
            :..    .|.|.   :...:|::||:.||:|..||.:|.|.|..|||.|.|..|.|.|:|::|..
 Worm   131 SRDYCDYSVAGT---LPLKDVVVVTLNYRVGILGFFTTGDTVCPGNFALWDLTLGLNWIQKHIES 192

  Fly   205 FGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFA- 268
            |||||..:||||||||.....:..|||.|..||:|||.|||.|...:|: .....||::..|||
 Worm   193 FGGDPGNITIFGQSAGAACVDLLALSPHSRDLFNRVIVMSGGALCEYAV-RTANSQAKVCYEFAR 256

  Fly   269 ----DVPDARNLSTVKLTKALRRINATKLLNA----GDGLKYWDVDHMTNFRPVVEEGLEVDAFL 325
                |..:::.|.....:|.|..|   :.:|.    ..|:..|..:...:|.|
 Worm   257 HLGYDGTNSQTLFNWMKSKPLEEI---EKMNGFQVPASGILAWTPNLDDDFFP------------ 306

  Fly   326 NAHPMDMLAQGMPTSIPLLLGTVPGEG------------AVRVVNILGNETLRQSFNLRFDELLQ 378
              ..:|.|..|.|.. .:::|....||            .:..:.:..||..::.....|:....
 Worm   307 --KSLDELRIGAPKK-DIMMGFAEHEGLFFEFLIKDPTPPLEALKLYVNEYYKKDTGDHFEATRN 368

  Fly   379 ELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTP 443
            :::||.:...:|..||.                  |.:..::.:.|..|...:::.. ||.....
 Worm   369 KIIEFYSRNVEDTDEKS------------------TKERLIDFVGDALFTAGVFDNA-KNCLKHG 414

  Fly   444 NPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVD 508
            |.|:||.|:|..|..:.:..........   .||.||.|:.... |:.|||....|.|:|.....
 Worm   415 NNVWLYIFDYCNPSGFGNQEEFMTFVAP---THCTDLRYVLGEG-LYSDFQPTEEEHKMIEKMTT 475

  Fly   509 YFVHFAKFGKPRNSES 524
            .:.:|||:|.|....|
 Worm   476 IYSNFAKYGNPNEHGS 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	146/533 (27%)
cest-28	NP_504691.2	COesterase	17..526	CDD:395084	148/536 (28%)