Protein Alignment Jhe and nlg-1

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001257226.1
• Gene: nlg-1 / 181484
• WormBaseID: WBGene00006412
• Length: 847
• Species: Caenorhabditis elegans
• Alignment Length: 664
• Identity: 162/664 - (24%)
• Similarity: 275/664 - (41%)
• Gaps: 157/664 - (23%)

  Fly     4 QRMLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKG--TNLQGYQSERFEAFMGIPYALP 66
            :|:..||||         |...:.:.|..:| ..|.|.::|  .:.:|........::||||.:.
 Worm     2 ERIYLLLLL---------FLPRIRSYDVRSV-TTSWGMVRGEVVSPEGDDLPPVAQYLGIPYGVA 56

  Fly    67 PIGDLRFSNPKV-------MPKLLGMYDASAPKMDCIQK------------------------NY 100
            |.|..|| |..:       |||     ||......|||.                        |:
 Worm    57 PTGQYRF-NMAISAAKWTHMPK-----DARKVSPVCIQTDMPELSETKRFRAFKHTSAQRFDFNH 115

  Fly   101 LLPTPVVYGDEDCLYLNVYRPE----IRKSALPVMVYIHGG--GFFGGSAGPGVTGPEYFMDSGE 159
            .|...:....|||||:|:|.||    .|.:.|||||.:||.  |:..|:|..|.|...|    |.
 Worm   116 RLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGWGTGNAFNGTTLAAY----GH 176

  Fly   160 VILVTMAYRLGPFGFLS-TQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVA 223
            :|:||:.||||.||||. .:.:..|||.|:.|...||..:...:..||||.:.||:.|..:|...
 Worm   177 IIVVTLNYRLGVFGFLGRCESSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASL 241

  Fly   224 AHMHLLSPRS---HGLFHRVISMSGTANVPFAIAEQPLEQARLLA-EFADVPDAR------NLST 278
            ..:.:.||.:   ..||.|.|.:.|:|..|:||::.|.:....|| |.|..|..|      |:.|
 Worm   242 VSLLMASPLTQPGRRLFRRAILLDGSALSPWAISQNPQQYFMQLAEELACAPKNRTSSFNDNVDT 306

  Fly   279 V----------KLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDML 333
            :          .:|||:.:|:....|              :.|.|:|:..|    ..|...:...
 Worm   307 IVRCMQVHSSENITKAVLKIDVPTFL--------------SGFAPIVDGQL----IPNKPQVSFS 353

  Fly   334 AQ--GMPTSIPLLLG--TVPGEGAVRVVNILGNETLRQSFNLR-----FDELLQELLEFPASFSQ 389
            .|  .:...|.||:|  :.|..      :::.||.|:...:..     |..|::.|.:|
 Worm   354 TQYGSLFREIDLLVGISSNPSH------HMISNEDLKVGISKEKRMRIFRSLVRNLYDF------ 406

  Fly   390 DRREKMMDLLVEVY--FQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPV------ 446
             .||:::..::..|  ::...:..:....|.:|.:||..:..||..|:..   |:.:.|
 Worm   407 -HREEILASIINEYTDWENPRDHPKSIRNGVLNALSDVLYTAPLIETLRS---HSADEVRKEANT 467

  Fly   447 YLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRN-----STEAKVIHSF 506
            ::::|.:: ..|::....::.:.|.   :..|.:.|:|..||...|.:..     :|:.|.|...
 Worm   468 FMFAFAHE-TRSWSQEQPNSGIRGS---LSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKV 528

  Fly   507 VDYFV-HFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFA----NAPDAYQGFEV----HVAS 562
            :.::| :|.|.|.|.....::       ::.|.|.. :|..|    :.|:.....|:    .|.:
 Worm   529 MMHYVSNFVKSGDPSKPNPMS-------KNFPMGDV-FHSTAWPQFDQPNREAYLEITDRPRVKN 585

  Fly   563 EFQTDRVNLWSHIL 576
            .::..:|..|::.:
 Worm   586 YYRNAQVGFWNNFI 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	144/569 (25%)
nlg-1	NP_001257226.1	COesterase	22..595	CDD:365897	154/629 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910