Protein Alignment Jhe and cest-3

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 138/587 - (23%)
• Similarity: 215/587 - (36%)
• Gaps: 173/587 - (29%)

  Fly    40 GCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPT 104
            |.|:|..:...|    ..|..:|:|.||:|.||||.|:.......:.:|:.....|...:.:...
 Worm    29 GKLEGKTVNVDQ----HMFKNVPFAKPPLGKLRFSLPEWTNPWKNIRNATEYSPSCFSNSSMRTD 89

  Fly   105 PVVYG-DEDCLYLNVYRPE--IRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDS--------G 158
            ...:. .||||||||:..|  ::......:||.||||....||       ..|.|:        .
 Worm    90 SNFFPMSEDCLYLNVFTNEYCLKSKNCSTVVYYHGGGINMDSA-------VQFNDTFILERYVKE 147

  Fly   159 EVILVTMAYRLGPFGFL-STQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGV 222
            .|:.:..|||||.||.| ...:.::..|..:.|..||||::.:.|..|||....:.:.|.|||
 Worm   148 NVVFIIPAYRLGIFGLLYFGSNNLVPQNLAIHDCELALRFIHQEISNFGGHKDDINLMGHSAG-- 210

  Fly   223 AAHMHLLSPRS------HGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDA--RNLST- 278
             ||:.|:...|      |.|.:|:|.:|     |....:.|....:...:||:....  ||::.
 Worm   211 -AHISLIFGFSRHIDPDHKLINRIIVLS-----PVPSYDMPELLIKNCYDFAERVGCYKRNVTAR 269

  Fly   279 -VKLTKALRRINATKLLN-----AGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGM 337
             .::.|.||:.:|..|::     ..|.|.:|:                   ||...|
 Worm   270 DTEIVKCLRKKDARGLMSMQRLMENDRLYFWN-------------------FLAGEP-------- 307

  Fly   338 PTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLV-E 401
                                           |..| ||.:.:..|:..     :|:.::...| |
 Worm   308 -------------------------------FMYR-DESIADFKEYAV-----KRDMLIGNTVDE 335

  Fly   402 VYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHK-NVCHTPNPV-YLYSFNYQG----PLSYA 460
            |.::...:.|......||:      ::.| |...|| |..|...|| ..|....||    ..:||
 Worm   336 VKWKRLKKENPAIAGSFMD------WENP-YEVAHKFNFYHDSAPVNSTYESFTQGIFVSTATYA 393

  Fly   461 SAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFV-----DY----------- 509
            .|..:|..|           :|||:|.      |:.|:....:..||     ||
 Worm   394 EAQANAGGT-----------VYLFQSN------QQPSSHVSDMQYFVGTHREDYHTSDMDIMDTF 441

  Fly   510 ----FVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVN 570
                .|:|.|||.|      :|....::.||      .:.:|...:..:|....:..:|....||
 Worm   442 YSKMIVNFTKFGSP------SPVWEPLVPSR------MNYYALEVNTEKGIWPRMEEDFHESDVN 494

  Fly   571 LW 572
            .|
 Worm   495 FW 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	129/540 (24%)
cest-3	NP_510042.2	Abhydrolase	23..496	CDD:304388	137/585 (23%)
		Aes	<118..>254	CDD:223730	44/150 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157110
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740