Protein Alignment Jhe and cest-9.1

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 581
• Identity: 143/581 - (24%)
• Similarity: 234/581 - (40%)
• Gaps: 99/581 - (17%)

  Fly    32 LTVCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCI 96
            |.|...|.|.|:|..:..........|..:|:|.||:|:|||:.|:......|:.|||.....|:
 Worm    18 LKVIQTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQNPESWSGILDASKYSPACM 82

  Fly    97 QKNYLLPTPVVYGDEDCLYLNVYRPE-IRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMD---S 157
            ..:....||..:..|||||:|::..| ...|..||:||.|||.:...||  .:....:.:|   :
 Worm    83 SNSSSTSTPQKHYSEDCLYINIFTSEKCLNSKCPVIVYFHGGAYNLDSA--IMFNDTFILDRYAA 145

  Fly   158 GEVILVTMAYRLGPFG--FLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAG 220
            .:|:.|..|.|||.||  :....| ::|.|..|.|...||.:|...|.:||||.:|||..|.|:|
 Worm   146 EDVVFVIPAVRLGVFGQLYFGPSD-LLSENLFLYDAVQALSFVHSEINYFGGDSKRVTAMGHSSG 209

  Fly   221 G----VAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAE----FADVPDAR-NL 276
            |    ......|:.| ...||.::|.:|.|.  .|...:..::.:..:.|    :....|.| |.
 Worm   210 GTIVDALGFSKLIDP-GVKLFQQMIVLSATG--MFGFYDMVVDNSFAIVEKFGCYNGTKDDRPNA 271

  Fly   277 STVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSI 341
            :..::...:|:|:..::|.....::  :||. .:||.|    |....||.::......:..|.|.
 Worm   272 NIAEMLDCMRQIDGREMLLMQRHME--EVDD-RDFRSV----LRGAPFLESNGKIADLKKSPPSR 329

  Fly   342 PLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQG 406
            .||.||.  |...|.|:.: |..:...| |.||.        |.:.::...|::|..| |....|
 Worm   330 NLLYGTT--EHEFRNVDHM-NPYISGIF-LDFDN--------PVAVARYYDEQLMANL-ETMING 381

  Fly   407 QHEVNELTVQGFMNLISDRGFKQPLYNT-----------------IHKNVCHTPNPVYLYSFNYQ 454
            ......:....|...:::.|....|:.|                 ||:.:.|.|:...|.:|
 Worm   382 DAAAIFICASTFSTAMANTGADVYLFETRQKPYSFHVSDMQYFVGIHREIYHRPDMDILDTF--- 443

  Fly   455 GPLSYASAYTSANVTG----KYGVVHCDDLLYL--------FRSPLLFPDFQRNSTEAKVIHSFV 507
                |:....:....|    ::..:..:.:.||        ...|::...|.....|.
 Worm   444 ----YSKLLVNFTKMGVPSPEWAPLDPERMNYLELKVDSDMKEGPVMLEGFHEKEMEL------- 497

  Fly   508 DYFVHFAKFG----KPRNSESLTPCSIEVLQSRPDGICDYHEFANAPD----AYQGF-EVH 559
             :|....:|.    |.|.|:.|.|..:::     :....|.|..|.|:    ..:|| .:|
 Worm   498 -WFGEMMEFDRNVTKIRQSQGLPPEHLDI-----ETQLKYWETTNKPEILTKTTKGFTSIH 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	133/536 (25%)
cest-9.1	NP_001359584.1	alpha/beta hydrolases	19..484	CDD:473884	125/497 (25%)