Protein Alignment Jhe and cest-26

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 169/599 - (28%)
• Similarity: 261/599 - (43%)
• Gaps: 132/599 - (22%)

  Fly    40 GCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGM-----YDASAPKMDCIQKN 99
            |.::|..::.......:.|:|||:|..|:|||||.||:......|:     :...||:.|...:.
 Worm    49 GLVEGFRIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAPQADFFWER 113

  Fly   100 YLLPTPVVYGDEDCLYLNVYRP-----EIRKSALPVMVYIHGGGFFGGSAGP-GVTGPEYFMDSG 158
            :.|.   |...||||||||:.|     |:.....|||||:|||||...||.. |..|...::...
 Worm   114 FTLG---VGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVKYGDEGIAKYLCRH 175

  Fly   159 EVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVA 223
            .|::||:.||||..||.||.|.|..||.||.|..:||:||:.|:..|||||::||:||||||||:
 Worm   176 GVVVVTIQYRLGLLGFFSTGDQVCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSAGGVS 240

  Fly   224 AHMHLLSPRSHGLFHRVISMSGTANVPFA-IAEQPLEQARLLAEFA-----DVPDAR--NLSTVK 280
            ..:..|||.|..|||:|:.|:|.....:: :.:..|..|  ..|||     |...||  |.|...
 Worm   241 VDLLSLSPHSRDLFHQVVPMAGNGECEWSTVGKNRLVNA--CREFAYRKCWDEKQARDENASESM 303

  Fly   281 L----TKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSI 341
            |    |:..|......|...|       ||       |.:.||::...:.:.|.|.|    |.||
 Worm   304 LEFLRTRKEREFEKRLLTRKG-------VD-------VSKIGLDLAPVIGSKPSDFL----PKSI 350

  Fly   342 P----------LLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMM 396
            .          :::||...||                  |.|..|      .|::|.:...:|::
 Worm   351 EELRKEAPKKNIMVGTCEHEG------------------LLFASL------GPSNFDEKGIDKLL 391

  Fly   397 DLLV----------------EVYFQ---GQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHT 442
            .||:                ::|.:   ...:..|:..:|::.|.||.......||...| :...
 Worm   392 ALLITEENHEDFEALREEAKKMYLKKLSDDEDDKEVAARGYIQLYSDLFVNNGTYNYAEK-MTKL 455

  Fly   443 PNPVYLYSFNYQGP-----LSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKV 502
            .|.|::|||:|..|     ||..:.:.:|        .||.:|.|:|...::| :::.|.::..:
 Worm   456 GNKVFMYSFDYCNPRSFGILSLRAPFRAA--------THCTELAYIFGVSIVF-NYRYNESDRAM 511

  Fly   503 IHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGF------EVHVA 561
            :......:.:|||:|.|..            |.....:.|:.....:.:....|      :..:.
 Worm   512 LDLMTKMWTNFAKYGNPNG------------QYEDSTVFDFKWEPTSKEEPTNFLAINEKKCEMQ 564

  Fly   562 SEFQTDRVNLWSHI 575
            :.:|.:|...|..|
 Worm   565 TVYQDNRAEFWKKI 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	162/543 (30%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	167/594 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	183	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.970