Protein Alignment Jhe and cest-2.1

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 162/628 - (25%)
• Similarity: 253/628 - (40%)
• Gaps: 156/628 - (24%)

  Fly     6 MLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFE----AFMGIPYALP 66
            :|.|.||..||.      .:::|..||     |.|.::|..|....|....    .|:|||:..|
 Worm     3 LLFLFLLSTLLH------ISISTRVQL-----STGTIEGKILTSTYSPLGNHTGIGFLGIPFVEP 56

  Fly    67 PIGDLRFSNPKVMPKLLGMYDASAPKMDCI---QKNYL--LPTPVVYGDEDCLYLNVYRPE--IR 124
            |.|:|||..|:......|:.:....|..|:   :|.|.  :..|:   .|||||.||:..:  ::
 Worm    57 PAGNLRFRKPRPPIPWDGILETKEYKPACMSDAKKTYKNGVGGPI---SEDCLYANVFTNQYCMK 118

  Fly   125 KSALPVMVYIHGGGFFGGSAGPGVTGPEY----FMDSG-EVILVTMAYRLGPFGFLSTQDAVMSG 184
            :....||:.:|||.....||  ....||.    |:..| .:::||..||||.|||     .|::|
 Worm   119 RKNCSVMIVVHGGRILTESA--SAFNPEILVNNFVGQGRNIVVVTFNYRLGTFGF-----GVLNG 176

  Fly   185 -----NFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMS 244
                 |.|:.|...|::|.::.:..|||:..::|:.|.||||........||.|.|:.::.|.||
 Worm   177 EKGDSNVGMFDMLEAVKWTRKEVHNFGGNKDKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMS 241

  Fly   245 GTANVPFAIAEQPLEQARLLAEFAD----------VPDA---RNLSTVKLTK---ALRRINATKL 293
            |.           |.|...||.|..          :|:.   |.||.|::.|   .||.|:|.::
 Worm   242 GA-----------LYQMGKLANFKGMTAMAQKAGCLPEVFGFRKLSQVRIDKTYSCLRNISAQEV 295

  Fly   294 LNAGDGLKYWDVDHMTNFRPVVEEGLEVDA-FLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVR-- 355
            |:|    :.|.:.:.|.:..|.    .:|. ||..:..::||.|....|..::||...|  :|
 Worm   296 LDA----QLWVLQNTTYYISVP----HIDGEFLLNYSDEILASGTIHPINSMIGTTTAE--LRDP 350

  Fly   356 -VVNILGNETLRQSFNLRFDELLQELLEF--------PASFSQDRREKMMDLLVEVYFQGQHEVN 411
             .:|.|.|...:       :|||:.|.|.        |..||:..::          |.|..:..
 Worm   351 IYINDLKNADKK-------EELLKNLCEHIGYELYTEPEEFSRKCQK----------FYGNGDDA 398

  Fly   412 ELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQ--GPL--SYASAYTSANVTGKY 472
            :.       |..|..|........:.:.... ..|::||::|:  ||.  .||.|....
 Worm   399 QF-------LADDMEFYDGSIKVANAHASKN-TKVFMYSYDYKDAGPAFKKYAQAPPPH------ 449

  Fly   473 GVVHCDDLLYLFRSPLLFPDFQRNSTEAKVI--HSFVDYFVHFAKFGKPRNS-----ESLTPCSI 530
               |.:||:|:|.:.      :.|.||...:  ..:...|..|..||.|..|     :..:|
 Worm   450 ---HSEDLIYVFGTS------RGNFTEKDYVIEQIYSGMFADFVNFGNPSPSKEQKWKEYSP--- 502

  Fly   531 EVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVNLWS 573
               :.|...:.|:.:....|....|:... |.||       ||
 Worm   503 ---EKREYFLIDFDKNFTMPGTRDGYYSR-ALEF-------WS 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	142/546 (26%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	153/601 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157011
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840