Protein Alignment Jhe and cest-35.2

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 157/543 - (28%)
• Similarity: 235/543 - (43%)
• Gaps: 88/543 - (16%)

  Fly    20 GPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLG 84
            |.|.:.|.......|...|.|.::| |:..:..:....::|||:|..|||||||..
 Worm     2 GGFLSHLKPEKNTEVFNASCGPIRG-NVYEHGDKIVNGYLGIPFAKAPIGDLRFKK--------- 56

  Fly    85 MYDASAPK----MDCIQKNYLLPTPVVYG-------------DEDCLYLNVYRPEIRK----SAL 128
              ...|.|    :||.:.....|.....|             :::||.|||:.|:.:.    :..
 Worm    57 --SVEAEKWTQPLDCYKYGPGCPQSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGF 119

  Fly   129 PVMVYIHGGGFFGGSAGP----GVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLK 189
            |||||.:||||..|.:..    .:||.   :...:|||||..||:||.||.:|.|.|..||:||.
 Worm   120 PVMVYFYGGGFEVGFSSMFDDYSLTGT---LPLKDVILVTPNYRIGPLGFFATGDDVARGNWGLW 181

  Fly   190 DQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIA 254
            ||.|||:|||::|:.|||||..|||.|.||||.:.....|||.::..|.:.|.|||.|..||.|.
 Worm   182 DQALALQWVQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIR 246

  Fly   255 EQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGL 319
            .:.:| ..:..|||:........:..|.:..:..::...|.| :|.| .....|.:|.|    ..
 Worm   247 SKDVE-GLIFREFANHHGYTGNDSKSLLQWYQSQDSEIFLKA-EGYK-CPASGMFSFVP----NF 304

  Fly   320 EVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNI----LGNETLRQSFNLRFDELLQEL 380
            :.|.|  ..|.|.|.:..|.     ||.:...|....:..    .|.:|.:|..:.   .|..|:
 Worm   305 DGDFF--PKPFDELRKEAPK-----LGAIVSIGEYEGLGFEDFYAGQKTPQQMLSA---ALGPEV 359

  Fly   381 LEFPASFSQDRREKMMDLLVEVYFQ-GQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPN 444
            :.        .||:::....|.|.: |.:|..|...:..:.:..|..|....::|: :::....|
 Worm   360 VR--------NREEVVKRAAESYLKNGGNENEENIAKTLVEIFGDYYFSVGAFDTV-RSLVKYGN 415

  Fly   445 PVYLYSFNYQGP-----LSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIH 504
            .||||||||..|     ......:.:||        |..||.|:|....  .:|.:.  :.:|:.
 Worm   416 TVYLYSFNYFNPNTPIVFGKNRPFNAAN--------HGSDLRYIFGEGT--GEFSKE--DRQVMD 468

  Fly   505 SFVDYFVHFAKFGKPRNSESLTP 527
            ....|..:|||:|.|.......|
 Worm   469 MMGTYHTNFAKYGNPNGKGVSVP 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	151/521 (29%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	154/531 (29%)
		Aes	<105..>239	CDD:223730	62/136 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157224
Domainoid	1	1.000	183	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.800