Protein Alignment Jhe and cest-32

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 612
• Identity: 166/612 - (27%)
• Similarity: 256/612 - (41%)
• Gaps: 140/612 - (22%)

  Fly    20 GPFCAALATVDQLTV----CPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPK--- 77
            |.|.:.|.....|.|    |.|.:|     |:..:..:....::|||:|..||.:|||..|.
 Worm     2 GGFLSHLKPEASLEVLNASCGPVIG-----NIYRHDDKIVNGYLGIPFAKAPICELRFKKPVEAE 61

  Fly    78 --VMPKLLGMYDASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPEIRK----SALPVMVYIHG 136
              ..|.....|....|:...:..|.|.|....:.:::||.||::.|..:.    :.||:|||.||
 Worm    62 KWTKPLNCHKYGPGCPQSGHMISNLLPPGYREFAEDNCLNLNIFAPSWKSEEFPNGLPIMVYFHG 126

  Fly   137 GGFFGGSAGPGVTGPEYFMDSG-----EVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALR 196
            |||   ..|......:|.: ||     :||:||..||:||.||::|.|.|..||:||.||.|||:
 Worm   127 GGF---EIGFSSMFDDYSL-SGTLPLKDVIVVTANYRVGPLGFMTTGDEVSRGNYGLWDQTLALK 187

  Fly   197 WVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQA 261
            |||.:|:.|||:|..||:.|.|||||:|.:..|||.|:.||||.::|||:|...|:|..:. ::|
 Worm   188 WVQEHIKSFGGNPNIVTVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRTKE-QEA 251

  Fly   262 RLLAEFA-----DVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEV 321
            .:...||     :..|:.:|                       |:::....::.|:.......:.
 Worm   252 EIFRNFAKHHGYEGEDSESL-----------------------LEWYKSQPLSKFQETATFEKKA 293

  Fly   322 DAFLN----------AHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDEL 376
            ..||.          ..|.|.|::..| .:..:......||       ||..|:.||.....|.:
 Worm   294 SGFLTFIPNFDGDFFPKPFDELSREAP-KLDAMATVDEYEG-------LGFLTMFQSRRNDMDII 350

  Fly   377 LQELLEFPASFSQDRREKMMDL---LVEVYFQGQHEVNELTVQ-GFMNLISDRGFKQPLYNTIHK 437
                   .:||..|..|..:|:   ::|.|.:...:.::..|: ..:.||||..|......|:..
 Worm   351 -------KSSFGSDVVENAVDVQKRIMEFYMKNIDKNDDKAVEKRLIQLISDSWFNIGALETVKT 408

  Fly   438 NVCHTPNPVYLYSFNYQGPLS---YAS--AYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNS 497
            :..:..| .||.||:|....|   ||:  .:.:||        |..:|.|:....:  ..|....
 Worm   409 STKYGSN-AYLGSFDYYNMGSNDPYATWFPFKAAN--------HGSELKYMLGEGM--GKFSPIE 462

  Fly   498 TEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPD---------AY 553
            .|.|||........:|.|:|                  .|:||       |.|:         .|
 Worm   463 EEFKVIDMMGTLTANFVKYG------------------NPNGI-------NGPELWKKYTPEKPY 502

  Fly   554 QGFEV-----HVASEFQTDRVNLWSHI 575
            ..|::     .:...||..|:.|:..|
 Worm   503 SYFKIDYPKSEMRDNFQDGRLKLFEDI 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	147/524 (28%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	157/584 (27%)
		Aes	<104..>227	CDD:223730	58/126 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157222
Domainoid	1	1.000	183	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790