Protein Alignment Jhe and cest-5.1

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 140/550 - (25%)
• Similarity: 217/550 - (39%)
• Gaps: 136/550 - (24%)

  Fly     7 LQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDL 71
            |:||||          ...:...|.| :...|.|.|:|..:..|     ..|..||:|.||:|:|
 Worm     4 LRLLLL----------IFIINAADSL-IIHTSFGHLEGAEIGDY-----HLFKKIPFAKPPVGNL 52

  Fly    72 RFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPE--IRKSALPVMVYI 134
            ||..|:...|..|:..|......|:..:....:|..:.|||||::|::..:  ::.....:.|||
 Worm    53 RFQKPEAAGKWDGIRSAIEYGPACMSNSSKTKSPQKWVDEDCLHVNIFTSKKCLKSRNCAIAVYI 117

  Fly   135 HGGGFFGGSAGPGVTGPEYFMDS--------GEVILVTMAYRLGPFGFLSTQDA-VMSGNFGLKD 190
            ||||....||       ..|.|:        .:||||...:|||.|...:..:. |...|..|.|
 Worm   118 HGGGLTYDSA-------VMFNDTVLLDTFVKRDVILVIPGFRLGIFSHFTVHNQNVAPNNLALYD 175

  Fly   191 QNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSP---RSHGLFHRVISMSGTANVPFA 252
            ..|||.:|:..|..|||:.|::|:||.|.||..|.|...|.   |...||.:.|.|||  ...|.
 Worm   176 ITLALEFVKSEIHSFGGNSQKITLFGHSYGGGLASMMTFSSEINRDLSLFQQAIVMSG--GFYFE 238

  Fly   253 IAEQPLEQARLLAEFAD--VP------DARNLSTVKLTKALRRINATKLLNAGDGLK---YWDVD 306
            ..:..:|..:...|:|:  ||      ..|:...:.:.|.|::::..:||.....|:   |.|
 Worm   239 ELKDHIEGTKRFVEYANCSVPLKLERKMERSQQEMYMMKCLQKLSGMELLRIQRLLEDKGYPD-- 301

  Fly   307 HMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNL 371
                |..|:   |....|.:....::|..  |.:||:|.|..                     ||
 Worm   302 ----FGGVI---LREPLFPDVKKFELLKS--PKNIPMLTGCT---------------------NL 336

  Fly   372 RFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRG---------- 426
            .||   .|.::.|..       |.::      |:...|.:|.......:.:.:||
 Worm   337 EFD---HESIKVPFG-------KYLE------FENPDECDEKYRNDVESGVENRGNHTDKTQGII 385

  Fly   427 --FKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLL 489
              .|..:.|.:..||     ..|||.:.|.                |:| .|.|||.|:    :.
 Worm   386 LPLKLQINNLLENNV-----TAYLYEYTYP----------------KHG-RHTDDLSYI----MG 424

  Fly   490 FPDFQRNSTEAKVIHSFVDYFVHFAKFGKP 519
            ...|:::..|..:...:.|..::|.|.|:|
 Worm   425 VHAFEKDENEVHLEQVYKDMVINFIKLGEP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	132/518 (25%)
cest-5.1	NP_501022.3	alpha/beta hydrolases	17..495	CDD:473884	134/526 (25%)