Protein Alignment Jhe and cest-12

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_499576.4
• Gene: cest-12 / 176642
• WormBaseID: WBGene00013540
• Length: 850
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 135/537 - (25%)
• Similarity: 206/537 - (38%)
• Gaps: 160/537 - (29%)

  Fly    38 SVGCLKGT------NLQGYQSERF----EAFMGIPYALPPIGDLRFSNPKVMPKL-LGMYDASAP 91
            :|.|.:|:      ||...||:.:    .||.||||...|:|:||...|:.:.:. ..::||:..
 Worm    36 TVSCSQGSVQGRQVNLGNDQSQLYSGQANAFTGIPYCQAPVGNLRLQPPQPLNQFNTTLHDATYF 100

  Fly    92 KMDCIQKNYLLPTPVVYGDEDCLYLNVYRPEI--RKSALPVMVYIHG-GGFFGGSAGPGVTGPEY 153
            :..|.|.|...||     :|||||||||.|:.  ..:.|.|:|.|.| .||..|       |.:.
 Worm   101 RPKCPQLNAGGPT-----NEDCLYLNVYTPQAGNTNANLSVLVLIDGSNGFSNG-------GCDQ 153

  Fly   154 FMDSG--------EVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQ 210
            ..:.|        ::::|||.||:|..||.:|....:..|.|:.||..|:||::..|..|||:|.
 Worm   154 NQEKGIISNLVQRQIVVVTMQYRIGALGFFTTYTNSVQSNLGMLDQVQAMRWIKTEIVNFGGNPN 218

  Fly   211 RVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSG--------TANVP----------------- 250
            ::|:.||..|..|...|.|||.|..||::.|..||        |..||
 Worm   219 QITVAGQDDGACAVSAHCLSPMSQNLFNQAIVQSGSVYSCYNPTPAVPTNPQVQVTTPRPMYDQS 283

  Fly   251 ------------FAIAEQPLEQARLL----AEFADVPDARNLSTVKLTKALRRI-----NATKLL 294
                        :....||:......    |::.|       .:.:|.:.|..|     |..:..
 Worm   284 NTGYGNAGYQNNYGYQPQPITSTSSYNSANAQYDD-------PSQQLAQTLCNISPDQWNNGQTQ 341

  Fly   295 NAGDGLKYWDVDHMTNFRP--------VVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGE 351
            |..:.:|.:.||...|.:|        :|.:    .:||.. .:|.|....| :||:::|||..|
 Worm   342 NIQNCMKNYTVDFFVNQQPGGPNATWMIVRD----TSFLPG-SIDSLTTRRP-NIPIIIGTVQDE 400

  Fly   352 GAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQ 416
            .|.....::.........||  |:.:         |...|:.|:          .|.:.|:::
 Worm   401 DADYAFKLINTGKGSDPNNL--DDWI---------FDFARKNKL----------NQTQANQVS-- 442

  Fly   417 GFMNLISDR----------------------GFKQPLYNTIHKNVCHTPNPVYLY-----SFNYQ 454
               |:||:.                      |..|.:.|..........|..|.|     ..|.|
 Worm   443 ---NIISNNYGVNTGALGQQGAQVNSQYQGSGTGQQVNNQYQNTQGQQTNNQYQYDQGGQQTNNQ 504

  Fly   455 GPLSYASAYTSANVTGK 471
            |      ||....|.|:
 Worm   505 G------AYYGGVVAGQ 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	134/535 (25%)
cest-12	NP_499576.4	Abhydrolase	37..>400	CDD:389770	109/387 (28%)
		Abhydrolase	<678..774	CDD:389770

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000