DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jhe and AADACL3

DIOPT Version :10

Sequence 1:	NP_523758.3	Gene:	Jhe / 36780	FlyBaseID:	FBgn0010052	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001096640.2	Gene:	AADACL3 / 126767	HGNCID:	32037	Length:	407	Species:	Homo sapiens

Alignment Length:	18	Identity:	9/18 - (50%)
Similarity:	10/18 - (55%)	Gaps:	2/18 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ACSLCCSLCPSSLKSNST 38
            ||.:|..|  .|.|||.|
Human    17 ACKVCGKL--FSHKSNLT 32

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	1/1 (100%)
AADACL3	NP_001096640.2	Abhydrolase_3	115..378	CDD:400284
AADACL3	NP_001096640.2	Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250\|UniProtKB:Q5NUF3	119..121
Blue background indicates that the domain is not in the aligned region.

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