Protein Alignment Jhe and Ces1g

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 614
• Identity: 169/614 - (27%)
• Similarity: 270/614 - (43%)
• Gaps: 133/614 - (21%)

  Fly    25 ALATVDQLTVC--------PPSVGCLKG------TNLQGYQSERFEAFMGIPYALPPIGDLRFSN 75
            ||:.: .||.|        ||.|..:.|      ..|:|: |:....|:|:|:|.||:|.|||:.
Mouse     5 ALSLI-SLTACLSLGHPSLPPVVHTVHGKVLGKYVTLEGF-SQPVAVFLGVPFAKPPLGSLRFAP 67

  Fly    76 PK-VMPKLLGMYDASAPKMDCIQ--------------KNYLLPTPVVYGDEDCLYLNVYRPE--I 123
            |: ..|.....:..|.|.: |.|              :..::|...   .|||||||:|.|.  .
Mouse    68 PEPAEPWSFVKHTTSYPPL-CYQNPEAALRLAELFTNQRKIIPHKF---SEDCLYLNIYTPADLT 128

  Fly   124 RKSALPVMVYIHGGGFF--GGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNF 186
            :.|.|||||:|||||..  |.|...||  |....::  |::|.:.||||.:||.||:|....||:
Mouse   129 QNSRLPVMVWIHGGGLVIDGASTYDGV--PLAVHEN--VVVVVIQYRLGIWGFFSTEDEHSRGNW 189

  Fly   187 GLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVP- 250
            |..||..||.|||.||..|||:|..|||||:||||.:..:.:|||.:..||||.|:.|.....|
Mouse   190 GHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPC 254

  Fly   251 -FAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTN---- 310
             |..|.:||  |:.:|..|   ..:..::..:...||:....:||.....:|:..||.:.:
Mouse   255 LFGRAARPL--AKKIAALA---GCKTTTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRES 314

  Fly   311 --FRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRF 373
              |.|.|.:|:    .|...|.::||:....::|.::|....|                     |
Mouse   315 YPFLPTVIDGV----LLPKAPEEILAEKSFNTVPYMVGINKHE---------------------F 354

  Fly   374 DELLQELLEFPASFSQ-DRR----------------EKMMDLLVEVYFQGQHEVNELTVQGFMNL 421
            ..::...|:||.|..: |::                ||::...:|.|..|..:...:| ..|::|
Mouse   355 GWIIPMFLDFPLSERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLGGTEDPATMT-DLFLDL 418

  Fly   422 ISDRGFKQP--LYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLF 484
            |.|..|..|  :.:..|::   ...|.|:|.:.|:.  |:.|......:.|.    |.|:|..::
Mouse   419 IGDIMFGVPSVIVSRSHRD---AGAPTYMYEYQYRP--SFVSDDRPQELLGD----HADELFSVW 474

  Fly   485 RSPLLFPDFQRNSTEAKVIHS--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFA 547
            .:|.|    :..::|.::..|  .:.::.:||:.|.|..                :|:..:.|:.
Mouse   475 GAPFL----KEGASEEEINLSKMVMKFWANFARNGNPNG----------------EGLPHWPEYD 519

  Fly   548 NAPDAYQ-GFEVHVASEFQTDRVNLWSHI 575
            ......| |.....|...:...|:.|:.:
Mouse   520 QKEGYLQIGVPAQAAHRLKDKEVDFWTEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	155/542 (29%)
Ces1g	NP_067431.2	COesterase	23..545	CDD:395084	163/590 (28%)