Protein Alignment Jhe and Ces1d

DIOPT Version :9

• Sequence 1: NP_001163166.1
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 598
• Identity: 170/598 - (28%)
• Similarity: 265/598 - (44%)
• Gaps: 130/598 - (21%)

  Fly    36 PPSVGCLKG------TNLQGYQSERFEAFMGIPYALPPIGDLRFSNPK-VMPKLLGMYDASAPKM 93
            ||.|..:||      .||:|: ::....|:|:|:|.||:|.|||:.|: ..|........|.|.|
Mouse    23 PPVVNTVKGKVLGKYVNLEGF-TQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPM 86

  Fly    94 DCIQ------------KNYLLPTPVVYGDEDCLYLNVYRPE--IRKSALPVMVYIHGGGFFGGSA 144
             |.|            .|.....|:.: .|||||||:|.|.  .:.|.|||||:|||||...|.|
Mouse    87 -CSQDAVGGQVLSELFTNRKENIPLQF-SEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGA 149

  Fly   145 ----GPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFF 205
                |..::..|      .|::||:.||||.:||.||.|....||:|..||..||||||.||..|
Mouse   150 STYDGLALSAHE------NVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANF 208

  Fly   206 GGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADV 270
            ||:|..|||||:||||.:..:.:|||.:..||||.||.||.:.....|.......|.|:|..:
Mouse   209 GGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKPIAGLVATLS-- 271

  Fly   271 PDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTN------FRPVVEEGLEVDAFLNAHP 329
             ..:..::..:...||:....:||.....|..:.:|.:.|      |.|.|.:|:    .|...|
Mouse   272 -GCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGV----VLPKAP 331

  Fly   330 MDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFP-ASFSQDRR- 392
            .::||:...:::|.::|          :|       :|.|..    ::..|:.:| |....|::
Mouse   332 EEILAEKSFSTVPYIVG----------IN-------KQEFGW----IIPTLMGYPLAEGKLDQKT 375

  Fly   393 ---------------EKMMDLLVEVYFQGQHEVNELTVQG--FMNLISDRGFKQP--LYNTIHKN 438
                           |.|:.::.|.|..|   .::||.:.  |.:|::|..|..|  :.:..|::
Mouse   376 ANSLLWKSYPTLKISENMIPVVAEKYLGG---TDDLTKKKDLFQDLMADVVFGVPSVIVSRSHRD 437

  Fly   439 VCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTE-AKV 502
            ...:   .|:|.|.|:.  |:.||.....|.|.:|    |::..:|.||.|........|. :|:
Mouse   438 AGAS---TYMYEFEYRP--SFVSAMRPKAVIGDHG----DEIFSVFGSPFLKDGASEEETNLSKM 493

  Fly   503 IHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGF-----EVHVAS 562
            :..|   :.:||:.|.|...                |:..:.|:    |..:|:     ....|.
Mouse   494 VMKF---WANFARNGNPNGG----------------GLPHWPEY----DQKEGYLKIGASTQAAQ 535

  Fly   563 EFQTDRVNLWSHI 575
            ..:...|:.|:.:
Mouse   536 RLKDKEVSFWAEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	160/539 (30%)
Ces1d	NP_444430.2	COesterase	24..545	CDD:278561	168/592 (28%)
		Aes	<121..>239	CDD:223730	58/123 (47%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850