Protein Alignment Jhe and Ces2a

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 543
• Identity: 165/543 - (30%)
• Similarity: 239/543 - (44%)
• Gaps: 75/543 - (13%)

  Fly    57 AFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQ---------KNYLLPTPVVYGDED 112
            ||:|||:|.||:|.|||:.|:......|:.|.::....|:|         |...|..|.:...||
Mouse    57 AFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQPDIMNLEDAKEMNLILPPISMSED 121

  Fly   113 CLYLNVYRPEIRK--SALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFL 175
            |||||:|.|...:  |.|||||:|||||...|||  .:........:.|:::|.:.||||..||.
Mouse   122 CLYLNIYTPTHAQEGSNLPVMVWIHGGGLVVGSA--SMNDVSKLAATEEIVIVAIQYRLGVLGFF 184

  Fly   176 STQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRV 240
            ||.|....||:|..||..||||||:||.:|||:..||||||.||||.:...|:|||.|.||||..
Mouse   185 STGDQHARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGA 249

  Fly   241 ISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDV 305
            |..||.|.:|..|::......:.:|         |||..:.|.:...|:.   |.|....:...:
Mouse   250 IMQSGVALLPDLISDTSEVVYKTVA---------NLSGCEATDSEALIHC---LRAKSKQEILAI 302

  Fly   306 DHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFN 370
            :.:....|.|.:|    .||..||.::|.......:|.::|....|....|...:|
Mouse   303 NQVFKMIPAVVDG----EFLPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMFMG--------- 354

  Fly   371 LRFDELLQELLE--FPASFSQDRREKMM-----DLLVEVYFQGQHEVNELTVQGFMNLISDRGFK 428
              .|.:::.:..  .||.........|:     .||||.|.....:...|..| |..::.|..|.
Mouse   355 --LDHIIKNITRETLPAVLKNTAARMMLPPECSHLLVEEYMGDTEDPETLQAQ-FREMLGDFMFV 416

  Fly   429 QPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDF 493
            .|.....|..  .:..|||.|.|.:..  |:......::|...:|    ||:.::|.|.|...:.
Mouse   417 IPALQVAHFQ--RSQAPVYFYEFQHLS--SFIKHVRPSHVKADHG----DDVAFVFGSYLWDMNL 473

  Fly   494 QRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEV 558
            .....|..:....:.|:.:||:.|.| |||.        |.|.|  :.|:.|      .|...:.
Mouse   474 DLTEEEELLKRMMMKYWANFARNGNP-NSEG--------LPSWP--VLDHDE------QYLQLDT 521

  Fly   559 H--VASEFQTDRVNLWSHILNEK 579
            .  |....:..|:..|:..|.:|
Mouse   522 QPAVGRALKARRLQFWTKTLPQK 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	154/487 (32%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:395084	162/534 (30%)