DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jhe and LOC100334697

DIOPT Version :9

Sequence 1:	NP_001163166.1	Gene:	Jhe / 36780	FlyBaseID:	FBgn0010052	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_002661384.2	Gene:	LOC100334697 / 100334697	-ID:	-	Length:	576	Species:	Danio rerio

Alignment Length:	591	Identity:	160/591 - (27%)
Similarity:	249/591 - (42%)	Gaps:	135/591 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPV 106
            :|...:||...::...|.|||:|.||:|..|:..|:.:....|:||||.|:..|:|   ....|:
Zfish    54 IKDGLVQGLLLDKSYVFYGIPFADPPVGTSRWKAPRPVTPWKGVYDASFPRAACMQ---ACIGPI 115

  Fly   107 VYG-----DEDCLYLNVYRPEIRKSA------LPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEV 160
            ...     .||||||||:.|.....|      ||||::||||.|..|||...:....:..:..:.
Zfish   116 ADDCPKKVSEDCLYLNVFVPLSVDLATPLLQPLPVMLWIHGGDFIAGSASKPLYDGRFISNYTQT 180

  Fly   161 ILVTMAYRLGPFGFL-STQD--AVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGV 222
            ::|::|||||.|||| |.:|  :...||:|:.||..||.|||:||..|||||.||||||:|||..
Zfish   181 VIVSIAYRLGAFGFLVSGKDPKSTAVGNYGILDQQAALIWVQQNIAAFGGDPSRVTIFGESAGAQ 245

  Fly   223 AAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPL----EQARLLAEFADVPDARNLSTVKLTK 283
            :..:||:...|..||.:.:..|    :||:|   ||    |..:|...||   .|.|.|...: |
Zfish   246 SVSLHLMIQSSKPLFKQAVFQS----LPFSI---PLKTRRESLKLGKHFA---KAANCSLEDM-K 299

  Fly   284 ALRRINA-----------TKLLNAGDGLKYWDVDHMTNFRPVVEEGL----EVDAFLNAHPMDML 333
            .|:.::|           :||:|....|:.:::     :.|.::..|    .|.||...|
Zfish   300 CLQSLSAEDVLHAQIKTSSKLVNPFRFLEVFEI-----WGPFIDGELIKEQAVSAFQKGH----- 354

  Fly   334 AQGMPTSIPLLLGTVPGEGAVRVVNILGNE------TLRQS--FNLRFDELLQELLEFPASFSQD 390
               .....|:||||...||.:.|..:....      |:..:  |.....::|::.|  |.....|
Zfish   355 ---WQKEKPVLLGTTSEEGVIFVYGVFKKPVSAVECTIYTTAIFKQHAIKILRKYL--PLYSDAD 414

  Fly   391 RREKMMDLLVEVYF--QGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFN- 452
            ||:.:..::.:..|  ..:.......:.|                          :..::|.|:
Zfish   415 RRDMLAQIVTDYIFWCPSRRSARAAVLSG--------------------------SSAWMYVFDQ 453

  Fly   453 -------YQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYF 510
                   :.|   .:|.|..        |.|..:|.::|.|..: .:|.....|..:.:..:.|:
Zfish   454 VSSDPRVWSG---VSSCYQR--------VCHGAELPFVFDSASV-ANFSMTPAEKLLSNRVLCYW 506

  Fly   511 VHFAKFGKPRNSESLTPCSIE--VLQSRPDGICDYHEFANAPDAYQGFEV-------HVASEFQT 566
            ..||..|.| ..|:..|..|.  ..|.||.....|       .|.:|:.:       |..:.:..
Zfish   507 GGFAHTGNP-TGETRRPSDISGFCRQQRPPSWPSY-------TANRGWMIMNLTAHPHSQAGYGE 563

  Fly   567 DRVNLW 572
            |..:.|
Zfish   564 DICDFW 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	149/535 (28%)
LOC100334697	XP_002661384.2	COesterase	44..569	CDD:278561	159/589 (27%)
LOC100334697	XP_002661384.2	Aes	<138..>245	CDD:223730	51/106 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575391
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840