Protein Alignment Jhe and nlgn1

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 674
• Identity: 178/674 - (26%)
• Similarity: 277/674 - (41%)
• Gaps: 168/674 - (24%)

  Fly    22 FCAALATV--DQLTVCPPSVGCLKGTNLQGYQSE-------RFEAFMGIPYALPPIGDLRFSNPK 77
            |...:|||  .:|....|.|....| .::|::.|       ....|:|:|||.||||:.||..|:
 Frog    36 FLLHIATVRSQKLDDVDPVVLTTYG-KVRGFKKELNNEILGPVVQFLGVPYAAPPIGERRFQPPE 99

  Fly    78 VMPKLLGMYDASAPKMDCIQKNYL---LP---TPVVYGD-------------EDCLYLNVYRP-- 121
             .|.:.|....|........:|.:   ||   .||.:.:             |||||||:|.|
 Frog   100 -PPTMWGDIKNSTQFAPVCPQNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTE 163

  Fly   122 -----------------------------------------EIRKSA--LPVMVYIHGGGFFGGS 143
                                                     :||.|.  .|||||||||.:..|:
 Frog   164 DVKRISKECARKPGKKICRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYMEGT 228

  Fly   144 AGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGD 208
            .  .|.........|.||::|:.||||..|||||.|....||:||.|...||||...||.|||||
 Frog   229 G--NVFDGSVLASYGNVIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENIGFFGGD 291

  Fly   209 PQRVTIFGQSAGGVAAHMHLLSPRSH---------GLFHRVISMSGTANVPFAIAEQPLEQARLL 264
            |.|:|:||..||....::..||..|.         |||.|.|:.||||...:|::.||.:.||:|
 Frog   292 PLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARIL 356

  Fly   265 AEFADVPDARNLS-TVKLTKALRRINATKLLNAG-DGLKYWDVDHMTNFRPVVEEGLEVDAFLNA 327
            |.....    |:| :.:|.:.|::....:|::.. ..::|    |:. |.||::..:..|
 Frog   357 ATKVGC----NMSDSGELVECLQKKPYRELVDQDIQPVRY----HIA-FGPVIDGDVIPD----- 407

  Fly   328 HPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRF---------------DELL 377
            .|..::.||...:..::||...|||...|.:.:.:|....|.:..|               .::|
 Frog   408 DPQVLMEQGEFLNYDIMLGVNQGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKDIL 472

  Fly   378 QELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNT--IHKNVC 440
            :|.::|..:...||...              |....|:   :.|.:|..:..|...|  :|.|.
 Frog   473 RETIKFMYTDWADRNNP--------------ETRRKTL---LALFTDHQWVAPAVATADLHSNF- 519

  Fly   441 HTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPL-----LFP-DFQRNSTE 499
              .:|.|.|:|.:........|:..|:        |.|::.|:|..|:     ||| :|.:|...
 Frog   520 --GSPTYFYAFYHHCQTDQVPAWADAS--------HGDEIPYVFGIPMIGPTELFPCNFSKNDVM 574

  Fly   500 AKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICD--YHEFANAPDAYQ--GFEVHV 560
            ...:  .:.|:.:|||.|.|...   .|...:.:.::|:...:  :..::.....|.  |.:..|
 Frog   575 LSAV--VMTYWTNFAKTGDPNQP---VPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRV 634

  Fly   561 ASEFQTDRVNLW------SHILNE 578
            ...::..:||||      .|::|:
 Frog   635 KEHYRATKVNLWLELVPRLHVMND 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	161/593 (27%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	169/644 (26%)