Protein Alignment Jhe and cel.2

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001120027.1
• Gene: cel.2 / 100144991
• XenbaseID: XB-GENE-1217488
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 558
• Identity: 167/558 - (29%)
• Similarity: 240/558 - (43%)
• Gaps: 118/558 - (21%)

  Fly    23 CAALATVDQLTVCPPSVGCLKGTN--LQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGM 85
            |..:|....|.|.....|.::|||  :.....:..:.|.|||:|.||   ..|...:..|...|.
 Frog    13 CLVVAHAKTLGVVHTEGGFVEGTNKKIGVVFPDYIDIFKGIPFAAPP---KPFEKAEKHPGWSGT 74

  Fly    86 YDASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPEIRKSA---LPVMVYIHGGGFFGGSAGPG 147
            ..|...|..|:|..  :....|:|..|||||||:.|:.|...   |||||:|.||||..|| |.|
 Frog    75 LQAKDYKPRCLQAT--ITQDNVFGSLDCLYLNVWVPQTRSQVSTNLPVMVWIFGGGFLLGS-GQG 136

  Fly   148 VT--------GPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRF 204
            ..        |.|..| .|:||:||..||:||.|||||.|:...||:||.||::|:.||:|||..
 Frog   137 ANFLSNYLYDGEEVAM-RGKVIVVTFNYRVGPLGFLSTGDSNAPGNYGLWDQHMAIAWVKRNIAA 200

  Fly   205 FGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLA---- 265
            |||||..:|:||:||||.:..:..|:|.:.||..|.||.||....|:||...||..|:.||
 Frog   201 FGGDPNNITLFGESAGGASVSLQTLTPYNVGLIKRAISQSGVGLCPWAIQRDPLTWAKSLASKLG 265

  Fly   266 -------EFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVD- 322
                   |.||.  .||.....||.|.:    .:|.|    |:| .:.|...:.||::.....|
 Frog   266 CPVNNTKELADC--LRNTDPGALTIAYQ----LQLFN----LEY-PLVHYLAYSPVIDGDFIPDE 319

  Fly   323 ---AFLNAHPMDMLAQGM---------PTSIPLL---LGTVPGEGAVRVVNILGNETLRQSFNLR 372
               .|.||..:|.:| |:         ...:|.:   |..:..|...:||..|   ||.:.
 Frog   320 PRNLFSNAAGVDYIA-GVNNMDGHLFAGVDLPAINQPLHKISTEQVQKVVRGL---TLAKG---- 376

  Fly   373 FDELLQELLEFPASFSQDRREKMMDLLVEVYFQG------QHEVNELTVQ---GFMNLISDRGFK 428
                      .||          :|:..::|..|      |.::....|:   .::.|::
 Frog   377 ----------VPA----------LDIAYDLYTAGWGTNPSQEDMKRTVVEVETDYIFLVA----- 416

  Fly   429 QPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKY----GVVHCDDLLYLFRSPLL 489
                         |...:.|:..|.:|..:|:..::..:....|    |..|.:||.::|..|..
 Frog   417 -------------TQEALALHYQNAKGAKTYSYMFSHPSRMPVYPSWMGADHAEDLQFMFGKPFS 468

  Fly   490 FPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTP 527
            .|...| ..:..|....:.|:.:||..|.|...||..|
 Frog   469 TPLAYR-PRDRDVAQYMIAYWTNFAATGDPSKGESSIP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	162/541 (30%)
cel.2	NP_001120027.1	COesterase	24..542	CDD:395084	164/547 (30%)