Protein Alignment Jhedup and Ces2el1

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001418901.1
• Gene: Ces2el1 / 688542
• RGDID: 1587637
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 171/570 - (30%)
• Similarity: 263/570 - (46%)
• Gaps: 89/570 - (15%)

  Fly     7 GVLLFVAVAVG-DSLD-VCLEDMGCMRGTLMPGYQSG-EFEAFMGIPFAQPPVGPLRLKNPVPNE 68
            |:||.|....| ||.. :.....|.:||:|:....:. :...|:|||||:|||||||...|...|
  Rat    16 GLLLLVLHVRGQDSASPIRNTHTGQVRGSLVHVKDTDIDVHTFLGIPFAKPPVGPLRFAPPEAPE 80

  Fly    69 PWEGVLDAGAAKDSCIQRSYFAKEWGLMG----------------VEDCLYLNVYRPKNRAE-DK 116
            ||.||.||.:....|:|..      .:||                .|||||||:|.|.:..| ..
  Rat    81 PWSGVRDATSHPAMCLQND------NMMGSEDMKIMKLILPPISMSEDCLYLNIYAPTHAHEGSN 139

  Fly   117 LPVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQR 181
            |||||:||||....|.| .|..| ..|..|..||:||:.||||..||.||||||..||:|:.||.
  Rat   140 LPVMVWIHGGALTVGMA-SMYDG-SMLAATEDVVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQV 202

  Fly   182 LALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKD 246
            .||:|:|::||.|||:|.:||:.|.||||.|...|::||.|:|||.      |.:..|.:.:|.|
  Rat   203 AALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVVSPMSQGLFH------GAIMESGVVVLPD 261

  Fly   247 PLSQARRLGKELA--IDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPS 309
            .:|::..:...:.  :....::.|:.|.:.||.....::|   |..||:..:|         |..
  Rat   262 LISRSSEMVYRIVANLSGCAAVDSETLMQCLRGKSEAEIL---DINKVFKIIP---------AVV 314

  Fly   310 PDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNE----NFLEHMAL 370
            ...||.:.|.:...:...:::|.|:.:::  .|....:...|.:.:...|...    ..|:..||
  Rat   315 DGEFLPKHPQELLASANFHRVPSIIGINN--DEYGWILPMIFDSAQKIEEITRKTLPTVLKSTAL 377

  Fly   371 LLNLPEGTPVQMVSEILDAYDFKGDSLNNDTM-LKLAEISGDFNFYYPIYETISSYVTYANLEEN 434
            .:.||......::.|      :.||:.:..|: .:..|:.|||.|..|..:.       |:.:.:
  Rat   378 KMMLPPECGDLLMEE------YMGDTEDPKTLQAQFREMMGDFMFVIPALQV-------AHFQRS 429

  Fly   435 PLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSL 499
            ...:|.:||...:|   ||......: :.|.|.|:........|....||...|:..:.:::...
  Rat   430 HAPVYFYEFQHRSS---FFKDVKPPH-VKADHGDEVFLVFGYLVGDIKFPHTEEEELLSRKIMKY 490

  Fly   500 MTDFAKTGVFHEESI--CKVSDFKEQGMCNYLHFGGNKEKYLE-DIRNSI 546
            ..:||:.|..:.|.:  ..|.|..:|              ||: ||:.|:
  Rat   491 WANFARHGNPNSEGLPHWPVMDHDDQ--------------YLQLDIQPSV 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	153/501 (31%)
Ces2el1	NP_001418901.1	COesterase	30..538	CDD:395084	164/556 (29%)