Protein Alignment Jhedup and Ces5a

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 527
• Identity: 150/527 - (28%)
• Similarity: 231/527 - (43%)
• Gaps: 95/527 - (18%)

  Fly    28 GCMRGTL------------MPGYQS---GEFE---AFMGIPFAQPPVGPLRLKNPVPNEPWEGVL 74
            |.|.|::            :.|.|:   |..|   .|:|||||.||:||||...|.|..||:.:.
Mouse    25 GAMAGSVTEEPHRYTKLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLR 89

  Fly    75 DAGAAKDSCIQRSYFAKEW------------GLMGV-EDCLYLNVYRPKNRAE-DKLPVMVYIHG 125
            :|.|..:.|.|.    .||            .::|: |||||||:|.|.:... ..|||||:|.|
Mouse    90 EATAYPNLCFQN----LEWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPG 150

  Fly   126 GGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKH 190
            |||.:|||.......  |.....|::||:.||||.|||.:|.::|.|||:.|.||..||.|::::
Mouse   151 GGFETGSASIFDGSA--LAVYEDVLVVTIQYRLGIFGFFTTQNQHAPGNWAFWDQLAALLWVREN 213

  Fly   191 IATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLG 255
            |..|||:|..||:.|:|||.||....::||.|..||..::..:|...:.::|...:.|
Mouse   214 IKYFGGNPDSVTIFGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDL------- 271

  Fly   256 KELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPS------PDAFL 314
                        ..|| :.:.|||...:..|...||.......|..:.:.:...      ..:|.
Mouse   272 ------------KHDL-QVVANVCDCNVSDSKALLKCLREKSSLELMSLSQKAKSFTRVVDGSFF 323

  Fly   315 VEDPLDAHRAGRINQMPWILSLSSR-AGEGSLFIMRAFINPKLRAEFNEN-FLEHMALLLNLPEG 377
            .|:||:......:..:|.|:.:::: .|    :|:.....|::....||: .|..:..||::
Mouse   324 SEEPLELLSQKTLKIVPSIIGVNNQECG----YILPVRDTPEILLGSNESTALTLIHTLLHI--- 381

  Fly   378 TPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFE 442
             |.|.:..:...| |.|.....|....|.::.||..|..|...|    ..|......|::.|.|:
Mouse   382 -PTQHLYIVTKEY-FHGKHSPTDIRDTLLDLFGDVFFVVPGLVT----ARYHRDSGGPVYFYEFQ 440

  Fly   443 ---FAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDD---FPKDSEDAKVIQR-MSSLM 500
               ....||...|         :.|.|.|:.......|....|   |.:.:|:.|::.| |....
Mouse   441 HRPHCFQNSRPAF---------VKADHTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYW 496

  Fly   501 TDFAKTG 507
            .:||::|
Mouse   497 ANFARSG 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	148/524 (28%)
		Aes	<106..>210	CDD:223730	47/104 (45%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	147/519 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832453
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940