Protein Alignment Jhedup and nlgn3b

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 585
• Identity: 148/585 - (25%)
• Similarity: 235/585 - (40%)
• Gaps: 108/585 - (18%)

  Fly    41 GEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQR------SYFAKEWGLMGV- 98
            |..:.::|:|:|.||||..|...|.....|.||.:|......|.|.      ......|....:
Zfish    68 GPVDQYLGVPYAAPPVGEKRFMPPDAPSAWSGVRNATRFPPVCPQTVRNAVPDIMMPVWATYNMD 132

  Fly    99 ----------EDCLYLNVYRP-----------------------KNRAEDKLPVMVYIHGGGFFS 130
                      |||||:|:|.|                       ::..:|..|||::||||.:..
Zfish   133 TVATYLQEQSEDCLYMNIYVPTQSGTKRTGDMSADTERTEDDGLRDSRDDPRPVMLFIHGGSYME 197

  Fly   131 GSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFG 195
            |:.:.|..  ..|.....|:::|:|||:|..|||||||:...||:|..||..||:||.|:|..||
Zfish   198 GTGNIMDG--SVLASYGNVIVITLNYRVGILGFLSTGDQAAKGNYGLLDQIQALRWINKNIGYFG 260

  Fly   196 GDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAI 260
            |||.:|||.|...|.....|..:|.:|:|||..::..:|:. ||:..:...|:...|.|.:.:.
Zfish   261 GDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSA-LSSWSVNYQPVKYTRLLAERVG- 323

  Fly   261 DQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMP---HLTTLPVLEAPSPDAFLVEDPLDAH 322
              ...|.:|||.     :|.:|.  |...|...:..|   |:...||::..    .:.:||....
Zfish   324 --CNVLDTQDLV-----LCMQKR--SYRELVEQEIQPARFHVAFGPVIDGD----LIPDDPEVLM 375

  Fly   323 RAGRINQMPWILSLSSRAGEGSLFIMRAFINPK----LRAEFNENFLEHMALLLNLPEGTPVQMV 383
            ..|..  :.:.:.|....|||..|: ...:.|:    ..::|:....:.:..|...|||... :.
Zfish   376 EQGEF--LNYDIMLGVNQGEGFRFV-EGVVEPEEGGVSGSDFDFTVSDFVDSLYGYPEGKDT-LR 436

  Fly   384 SEILDAYDFKGDSLNNDTMLK-LAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLN 447
            ..|...|....|..|.:|..| |..:..|..:..|...|...:..|.    :|.|.|.|.....:
Zfish   437 ETIKFMYTDWADRDNPETRRKTLVAMFTDHQWVEPAVVTADLHARYG----SPTFFYAFYHHCQS 497

  Fly   448 SITKFFAGTTDDYGLGAVHMDDGLHTIRIPV--SFDDFPKD--SEDAKVIQRMSSLMTDFAKTG- 507
            .:...:|        .:.|.|:..:...:|:  ..:.||.:  ..|..:...:.:..|:|||||
Zfish   498 PMKPPWA--------DSAHGDELPYVFGVPLIGPTELFPCNFSRNDIMLSAVVMTYWTNFAKTGD 554

  Fly   508 ----------VFHEESICKVSDFKEQGMCNYLHFGGNKEKYLE-----DIRNSITLTAFPIWKKL 557
                      ..|    .|.:.|:|   ..:..:|.:.:.||.     .:|:....|....||.|
Zfish   555 PNKPVPQDTKFIH----TKANRFEE---VTWAKYGPHDQLYLHIGLKPRVRDHYRATKVAFWKHL 612

  Fly   558  557
            Zfish   613  612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	136/529 (26%)
nlgn3b	XP_005165239.1	COesterase	45..609	CDD:395084	145/580 (25%)
		Herpes_BLLF1	<753..>843	CDD:282904