Protein Alignment Jhedup and ces2a

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 561
• Identity: 172/561 - (30%)
• Similarity: 249/561 - (44%)
• Gaps: 153/561 - (27%)

  Fly    18 DSLDVCLEDMGCMRGTLMPGYQS-GEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKD 81
            ||..|.:...|.:||..:....| ...|.::|||||||||||.||..|.|.:.|||:.:|.....
Zfish    24 DSGPVAVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEHPL 88

  Fly    82 SCIQR----SYFAK----EWGLMGV-EDCLYLNVYRPKNRAE-DKLPVMVYIHGGGFFSGSA--- 133
            .|:|.    ...||    |...:|| |||||||||.|..||| :|||||::|||||...|.|
Zfish    89 MCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEKLPVMIWIHGGGLAMGGACMF 153

  Fly   134 --------HPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKH 190
                    .|:|:       ..|||:|.:.||||..|:.||||:|..||:||.||..||||:|::
Zfish   154 KELCLYDGTPLAA-------YEKVVVVVIQYRLGILGYFSTGDQHAKGNWGFLDQIAALQWVQQN 211

  Fly   191 IATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLG 255
            |..|||||:.||:.|.|||||||.|..:||.:|||||.::..:|...:... .:|||.:.|:.:.
Zfish   212 IEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGY-FVKDPSTHAQVIA 275

  Fly   256 KELAIDQAESLSSQDLAEALRNVC---------------------------PKKLLVSVDSLKVW 293
            .   |.:.:..||:.|.:.:|.:.                           |:::|.|.|..||
Zfish   276 N---ITECDFSSSEVLVKCIREMTEEQIIKAAQKKGIFPGAAVDGEFIKAQPEEILKSKDFQKV- 336

  Fly   294 DNMPHLTTLPVLEAPS--------PDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRA 350
                     |:|...:        |..||.::              |:..:.::|.:..|.::.|
Zfish   337 ---------PILIGTTNHEFGWMLPQIFLPKE--------------WVKGMDTKAAKDRLGLLNA 378

  Fly   351 ----FINPKLRAEFNENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGD 411
                ..|..:..|:.:|        ...||        ||.||:               .|:.||
Zfish   379 DGASGANGIIADEYFKN--------AKTPE--------EIRDAF---------------TELLGD 412

  Fly   412 FNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKF-----FAGTTDDYG--LGAVHMD- 468
            .....|.. |::||...|.:   |:::|.|:. |.::..||     .|...||.|  .||...|
Zfish   413 IFMVIPSI-TVASYHREAGV---PVYMYEFQH-GPSTANKFRPSFVKADHADDVGFVFGACFWDV 472

  Fly   469 --DGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTG 507
              .||.|:           ..|:.::.:.:.....:|.:||
Zfish   473 HVKGLGTL-----------TEEENQLCRTVMKYRANFIRTG 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	168/548 (31%)
ces2a	NP_001070720.1	COesterase	25..541	CDD:395084	171/560 (31%)