Protein Alignment Jhedup and nlgn3a

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 620
• Identity: 157/620 - (25%)
• Similarity: 246/620 - (39%)
• Gaps: 131/620 - (21%)

  Fly    28 GCMRGTLMPGYQS--GEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA 90
            |.:||..:|.:..  |..:.::|:|:|.||||..|...|.|...|.|:.:|......|.|..:.|
Zfish    76 GKLRGARVPLHSEILGPVDQYLGVPYATPPVGEKRFLPPEPPSSWSGIKNATHFAPVCPQNIHNA 140

  Fly    91 KEWGLMGV-----------------EDCLYLNVYRP---------------------------KN 111
            ....:|.:                 |||||||:|.|                           |.
Zfish   141 VPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKICRKGGTHSKK 205

  Fly   112 RAED----------------KLPVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGP 160
            :.||                ..|||||||||.:..|:.: |..| ..|.....|:::|:|:|:|.
Zfish   206 QGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEGTGN-MIDG-SVLASYGNVIVITLNFRVGV 268

  Fly   161 FGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGL 225
            .|||||||:...||:|..||..||:||.::|..||||..::||.|...|.....|..:|.:|:||
Zfish   269 LGFLSTGDQAAKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSLLTLSHHSEGL 333

  Fly   226 FQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSL 290
            |..::..:|:. ||:..:...|:...|.|.:::..:..::|   |:.:.||....::|:..
Zfish   334 FHRAIIQSGSA-LSSWAVNYQPVKYTRLLAEKVGCNVLDTL---DMVDCLRKKSARELVEQ---- 390

  Fly   291 KVWDNMP---HLTTLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFI 352
               |..|   |:...||::..    .:.:||......|..  :.:.:.|....|||..|:.....
Zfish   391 ---DIQPARYHVAFGPVIDGD----VIPDDPEILMEQGEF--LNYDIMLGVNQGEGLRFVENVVD 446

  Fly   353 NPK--LRAEFNENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLK-LAEISGDFNF 414
            :..  ...:|:.:..:.:..|...|||... :...|...|....|..|.:|..| |..:..|..:
Zfish   447 SEDGVSGNDFDFSVSDFVDSLYGYPEGKDT-LRETIKFMYTDWADRDNPETRRKTLVALFTDHQW 510

  Fly   415 YYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPV- 478
            ..|...|...:..|.    :|.:.|.| :....|:.|  ...:|     |.|.|:..:...||:
Zfish   511 VEPSVVTADLHARYG----SPTYFYAF-YHHCQSLMK--PAWSD-----AAHGDEVPYVFGIPMI 563

  Fly   479 -SFDDFPKD--SEDAKVIQRMSSLMTDFAKTG-----------VFHEESICKVSDFKEQGMCN-- 527
             ..|.||.:  ..|..:...:.:..|:|||||           ..|    .|.:.|:|.....
Zfish   564 GPTDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIH----TKANRFEEVAWSKYN 624

  Fly   528 -----YLHFGGNKEKYLEDIRNSITLTAFPIWKKL 557
                 |||.|....     :|:....|....||.|
Zfish   625 PQDQLYLHIGLKPR-----VRDHYRATKVAFWKHL 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	143/559 (26%)
		Aes	<106..>210	CDD:223730	47/146 (32%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:306613	154/615 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575367
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840