Protein Alignment Jhedup and Ces2h

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 524
• Identity: 157/524 - (29%)
• Similarity: 247/524 - (47%)
• Gaps: 69/524 - (13%)

  Fly     7 GVLLFVAVAVGDSLD-VCLEDMGCMRGTL--MPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNE 68
            |:||.:.|...||.. :.....|.:.|:|  |.....| ..:|:|||||:|||||||...|.|.|
Mouse    16 GLLLLLRVQGQDSTSPIRTTHTGQILGSLIHMKDLDVG-VHSFLGIPFAKPPVGPLRFAPPEPPE 79

  Fly    69 PWEGVLDAGAAKDSCIQ--RSYFAKEWGLMGV--------EDCLYLNVYRPKNRAE-DKLPVMVY 122
            ||.||.|..:....|:|  .:...:.:.|:.:        |||||||:|.|.:..| ..|||||:
Mouse    80 PWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYAPDHAHEGSNLPVMVW 144

  Fly   123 IHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWI 187
            ||||....|.| .|..| ..|.....||:||:.||||..||.|||||...||:|:.||..||:|:
Mouse   145 IHGGSLVIGMA-SMYDG-SMLAAMENVVVVTIQYRLGVLGFFSTGDERARGNWGYLDQVAALRWL 207

  Fly   188 QKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAM-KILKDPLSQA 251
            |::||.|||:|.:||:.|.||||.|....::||.|:|||:.::..:|...:|:: .:..|.:.|.
Mouse   208 QQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALISSLISVSSDVVYQT 272

  Fly   252 RRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVE 316
                 ...:...|.:.|:.|...||....::::....:.|:   :|.:.         ...||..
Mouse   273 -----VANLSGCEQVDSEALVNCLRGKSEEEIMAINKAFKI---IPGIV---------DGIFLPR 320

  Fly   317 DPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPK--LRAEFNENFLEHMALLLNLPEGTP 379
            .|.:...:...:.:|.|:.:::......:....:.|:.|  :..:..:..|:..|..:..|
Mouse   321 HPQELMASADFHPVPSIIGVNNDEYGWIIPSSMSMIDSKKGMDRQMVQAILQRRATQMMWP---- 381

  Fly   380 VQMVSEILDAYDFKGDSLNND---TMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIF 441
             ..||::| ..::.||  |.|   ..::..|:..||.|..|..:......::|     |:|.|.|
Mouse   382 -PEVSDLL-MEEYMGD--NEDPQFLQVQFKEMMKDFTFVIPALQVAQFQRSHA-----PVFFYEF 437

  Fly   442 EFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSF-----DDFPKDSEDAKVIQRMSSLMT 501
            :..     ..||..:...: :.|.|.|:.|...|   ||     .||.::.|  .:.:||.....
Mouse   438 QHR-----PSFFKDSKPSH-VKADHGDEILFIFR---SFWGGTQVDFTEEEE--LLSRRMMKYWA 491

  Fly   502 DFAK 505
            :||:
Mouse   492 NFAR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	150/499 (30%)
		Aes	<106..>210	CDD:223730	52/104 (50%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	151/510 (30%)
		Aes	<127..>230	CDD:223730	52/104 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840