Protein Alignment Jhedup and alpha-Est2

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 153/495 - (30%)
• Similarity: 238/495 - (48%)
• Gaps: 43/495 - (8%)

  Fly    28 GCMRGTLMPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFAKE 92
            |..|.|:   |....:.||.|||:|:||||.||.:.|.|.|||:|||:....:...:||:...
  Fly    44 GLQRKTV---YDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNMLL-- 103

  Fly    93 WGLM-GVEDCLYLNVYRPKNRAEDKLPVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNY 156
             |:: |.||||:||||....::|..|||:|:|:||||..|.|......|:|.| ...||.|.:||
  Fly   104 -GIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFM-KKPVVFVAINY 166

  Fly   157 RLGPFGFLSTGDEHM--PGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMIS 219
            ||...||||..|..:  |||.|.|||.:||:||.::||.|.|||..:|::|.|||..|.|:.|.:
  Fly   167 RLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTT 231

  Fly   220 PNSKGLFQNSMSLTGTMFLSAMKILKDPLSQ-ARRLGKELAIDQAESLSSQDLAEALRNVCPKKL 283
            ..::|||..::..:|   .:..:.::.|.:. |.||.:.|.....|  ...|:...|..||.::
  Fly   232 EQTRGLFHKAIMQSG---CALSEWVESPDNNWAFRLAQNLGYKGDE--KDADVLSFLSKVCARQ- 290

  Fly   284 LVSVDSLKVWDNMPHLTTL------PVLEAPSPDAFLV---EDPLDAHRAGRINQMPWILSLSSR 339
            :.::|...:  |:..:.:.      ||:|....|..:|   ...|.:...|  |.:|.|:..:|.
  Fly   291 IAAIDQDVI--NLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWG--NDIPVIVGGNSF 351

  Fly   340 AGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLK 404
            .|..|..::|.  :|.....|: |.|.......:..||..: :|..:...| |..:...:..|.:
  Fly   352 EGLFSYQLVRK--DPWALKNFH-NILPREVRETSSLEGQDL-LVRRLKQLY-FNNEMQESMEMFE 411

  Fly   405 LAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAG--LNSITKFFAGTTDDYGLGAVHM 467
            ...|......::..:..|.:..:||  .:.|.::|.|:|..  .|...:...|   |...|..|.
  Fly   412 ALNIFSHRQIWHDTHRFILARQSYA--PKTPTYLYRFDFDSPHFNQFRRLVCG---DRIRGVAHA 471

  Fly   468 DDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTG 507
            |: |..:...:......|.|.:.|.|:||..:.|.||.:|
  Fly   472 DE-LSYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	152/492 (31%)
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	153/495 (31%)