Protein Alignment Jhedup and Est-P

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 155/557 - (27%)
• Similarity: 270/557 - (48%)
• Gaps: 54/557 - (9%)

  Fly     9 LLFVAVAVGDSLDVCLE-DMGCMRGTLMPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVP-NEPWE 71
            ||::|....::..:.:| ..|.:||.     .:|.:.::..||.|:.|.|.||.:.|.| :..|.
  Fly    12 LLWIAALESEADPLIVEITNGKIRGK-----DNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWT 71

  Fly    72 GVLDAGAAKDSCIQRSYFAKEWG-LMGVEDCLYLNVYRPKNRAEDKLPVMVYIHGGGFFSGSAHP 135
            .|.:|..:...|:|.:.|..|.. |||.||||.:::|:||.......||:|.:|||.|..||.
  Fly    72 DVFNATQSPVECMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSG-- 134

  Fly   136 MASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKK 200
            ...|.:.:|....:::|.:::.|||.||.||||.|:|||:|.||||||||||:|:||.|||.|..
  Fly   135 SIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDN 199

  Fly   201 VTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQAES 265
            :.::||||||.||||.::..:.|.|.:.::|::|.. |....|.:....:|..||:  .:....:
  Fly   200 IVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNA-LDPWVIQQGGRRRAFELGR--IVGCGHT 261

  Fly   266 LSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLE-APSPDAFLVEDPLDAHRAGRINQ 329
            ..|.:|.:.|::.....::.:|.|..|:..:|.....||:| :.:|||||.|||....::|:..|
  Fly   262 NVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQ 326

  Fly   330 MPWILSLSSRAGEGSLFIMRAFINPKLRAE-----FNENFLEHMALLLNLPEGTPVQMVSEILD- 388
            :||.::.::.  :|.....:.....||..|     .|:.:.:....||...:..  :.:.::.|
  Fly   327 VPWAVTYTTE--DGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAK--KTIKDMDDL 387

  Fly   389 AYDFKGDSLNN-----DTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNS 448
            ::|.:...|.:     ::...:..:..|..|...:...|..:..|.   ::|::.::::....:.
  Fly   388 SFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYG---KSPVYSFVYDNPTDSG 449

  Fly   449 ITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFA----KTGVF 509
            :.:..:..||.: .|.||.||................|.|  .:.::...::.|||    .|..|
  Fly   450 VGQLLSNRTDVH-FGTVHGDDFFLIFNTAAYRTGIRPDEE--VISKKFIGMLEDFALNDKGTLTF 511

  Fly   510 HEESICKVSDFKEQGMCNYLHFGGNKE-KYLEDIRNS 545
                          |.||:.:...:|| :.|...||:
  Fly   512 --------------GECNFQNNVNSKEYQVLRISRNA 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	141/494 (29%)
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	152/543 (28%)