Protein Alignment Jhedup and Ces1b

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 573
• Identity: 155/573 - (27%)
• Similarity: 246/573 - (42%)
• Gaps: 94/573 - (16%)

  Fly    31 RGTLMPGYQSGE-FE----AFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRS--- 87
            :|.::..|.|.| ||    .|:|:|||:||:|.||...|.|.|||..|.:|.:....|.|.:
Mouse    30 QGKILGKYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMCSQDAVAV 94

  Fly    88 ------YFAKEWGL--MGVEDCLYLNVYRPKNRAEDK-LPVMVYIHGGGFFSG----------SA 133
                  ...|:..:  :..|||||||:|.|.:..:.. |||||:|||||..:|          ||
Mouse    95 QLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTGGASLYNGLALSA 159

  Fly   134 HPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDP 198
            |            ..||:||:.||||.:|..||||||..||:...||..||:|:|.:||.|||:|
Mouse   160 H------------ENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNP 212

  Fly   199 KKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELA-IDQ 262
            ..|||.|.||||:|..:.::||.:|.||..::| ..::.|..:.|..|.:  |..|.:.:| :..
Mouse   213 DSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAIS-ESSVVLENIVITLDLV--ACDLSQMIATVSG 274

  Fly   263 AESLSSQDLAEALRNVCPKKLL---VSVDSLKVW-------DNMPHLTTLPVLEAP-SPDAFLVE 316
            ....||..:.:.||.....:||   |.::..||.       ||....|.:..:..| :|:..|.|
Mouse   275 CNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSMSTVIDGVVLPKAPEEILAE 339

  Fly   317 DPLDA--HRAG-RINQMPWIL--SLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPE 376
            .....  :..| ...:..||:  .|.....||           |:..|.....|......||:.|
Mouse   340 KSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEG-----------KMNEETASLLLRRFHSDLNISE 393

  Fly   377 GTPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIF 441
                .::..:::.| .:|    .|...|..::..|  .:..::..|.:.:...:|.:..:..|::
Mouse   394 ----SLIPAVIEKY-LRG----TDDPAKKRDLLLD--MFSDVFFGIPAVLLSRSLRDAGVSTYMY 447

  Fly   442 EFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKT 506
            ||....|    |........:...|.|:......||:..:.  ...|:..:.:.:.....:||:.
Mouse   448 EFRYRPS----FVSDKRPQTVEGDHGDEIFSVFGIPLLKEG--TSEEETNLSKMVMKFWANFARN 506

  Fly   507 GVFHEESICKVSDFKEQGMCNYLHFGGNKEKYLEDIRNSITLTAFPIWKKLFA 559
            |..:.|.:....::.|:.  .||..|...::     ...:.......|.:|.|
Mouse   507 GNPNGEGLPHWPEYDEKE--GYLQIGATTQQ-----AQRLKAEEVAFWTELLA 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	146/520 (28%)
Ces1b	NP_001074841.1	COesterase	22..547	CDD:395084	152/566 (27%)