Protein Alignment Jhedup and Gli

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 158/544 - (29%)
• Similarity: 247/544 - (45%)
• Gaps: 118/544 - (21%)

  Fly    41 GEFEAFMGIPFAQPPVGPLRLKNPVPNEPWE--GVLDAGAAKDSCIQR-SYFAKEWGLMGV-EDC 101
            ||...|:|||:|.||....|.|.|..:..|:  ..:|.|.|   |.|. .|.....|:|.: |||
  Fly   173 GECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPA---CPQPVRYTGATKGIMDMDEDC 234

  Fly   102 LYLNVYRPKNRA--EDKLPVMVYIHGGGFFSGSA-----HPMASGPEYLMDTNKVVMVTMNYRLG 159
            ||||||.||..|  ..|.|||||||||.|..|::     |.:||..:       ||:||:|||||
  Fly   235 LYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYD-------VVVVTLNYRLG 292

  Fly   160 PFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKG 224
            ..||||||||:.|||:|..||.:||:|:..:|..|.||...:|:.|..|||.||.|.|::|.::.
  Fly   293 ALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRN 357

  Fly   225 LFQNSMSLTGTMFLSAMKILKDPL---SQARRLGKEL--AIDQAESLSSQDLAEALRNVCPKKLL 284
            :.:..::.:|:. |:...:::|..   :.:|.||:.|  :|:     ||..|...||.   .:..
  Fly   358 IVRRVIAQSGSA-LADWALIQDKYRAQNTSRVLGQLLGCSIE-----SSWKLVNCLRT---GRSF 413

  Fly   285 VSVDSLKVWDNMPHLTTLPVLE----APSPD----------AFLVEDPLDAHRAGRINQ-MPWIL 334
            ..:.:.:....:......|||:    .|..|          .||.:.|....|||:.|: :.::.
  Fly   414 YELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMT 478

  Fly   335 SLSSRAGEGSLFI-MRAFINPKLRAE---FNENFLEHM---ALLLNLPEGTPVQMVSEILDAYDF 392
            .::::  |.:.|: ....::|....:   |::...||:   ...|| |.|    :...|...|.|
  Fly   479 GVTTQ--EAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLN-PNG----VYEAIKYIYTF 536

  Fly   393 KGDSLNNDTMLKLAEISGDFNFYY--PIYETISSYVTYANLEEN-PLFIYIFE--FAGLN----- 447
            ..|. ||:|:::...|:...:.||  |:.:.:.     ..||:. |:::|:..  ...||
  Fly   537 WPDP-NNNTIIRDQYINMLSDLYYRAPVDQMVK-----LMLEQKVPVYMYVLNTTVEALNLPQWR 595

  Fly   448 ----SITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTGV 508
                .|.::|.       .||..||.           :.|||...    :||  ::.||..:
  Fly   596 KYPHDIERYFL-------TGAPFMDT-----------EFFPKKEH----LQR--NMWTDNDR--- 633

  Fly   509 FHEESICKVSDFKEQGMCNYLHFG 532
                   .:|.|..|...|:..:|
  Fly   634 -------NMSHFFMQTYTNFARYG 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	153/518 (30%)
Gli	NP_476602.1	COesterase	137..695	CDD:395084	158/544 (29%)
		PRK13335	818..>918	CDD:139494