Protein Alignment Jhedup and cest-9.2

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 141/558 - (25%)
• Similarity: 217/558 - (38%)
• Gaps: 107/558 - (19%)

  Fly     8 VLLFVAVAVGDSLDVCLEDMGCMRGTLMPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEG 72
            :|||..:   .||.|.....|.:||.......:.....|..:|||:||:|.||...|...:.|.|
 Worm    12 ILLFPDI---QSLKVIETSYGRVRGITEWSDDNNHKYMFKSVPFAKPPIGKLRFAPPQYPDSWSG 73

  Fly    73 VLDAGAAKDSCIQRSYFAKEWGLMGVEDCLYLNVYRPKNRAEDKLPVMVYIHGGGFFSGSAHPMA 137
            ||||.....:|:..|...........|||||:|::..:.....|..|:||.|||.:...||....
 Worm    74 VLDASKYSPACLSNSSTTSTPQEHVSEDCLYINIFTSEKCLRSKCAVIVYFHGGAYNGDSATMFP 138

  Fly   138 SGPEYLMD---TNKVVMVTMNYRLGPFGFLSTGDEH-MPGNFGFKDQRLALQWIQKHIATFGGDP 198
            .  .::::   ...|::.....|||.||.|..|... :..|....|...||.::...|..|||||
 Worm   139 D--NFILERYVAEDVILAIPGVRLGVFGQLYFGPSALLTENLFMFDAVQALDFVHNEIPNFGGDP 201

  Fly   199 KKVTVLGHSAGGISAHL----HMISPNSKGLFQNSMSLTGTMFLSAMKILKD-PLSQARRLGKEL 258
            |:||::|||:||.....    :.:.|:.| |||..:.|:||.......:|.| ....:.:||  .
 Worm   202 KQVTIMGHSSGGTLVEALGFSNSVDPDLK-LFQQIIVLSGTGMFGFYDLLVDNSFIISEKLG--C 263

  Fly   259 AIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDAHR 323
            .....|..:..::||.|.  |.::    :|..::.....|:..:..|...|    |:........
 Worm   264 FNGTQEERTDANIAEILE--CMRQ----IDGHEIVGMQKHMEDVYKLTFKS----LLRGAPFMEL 318

  Fly   324 AGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFN---ENFLEHMALLLNLPEGTPVQMVSE 385
            .|:|.:.     .:|.:...::|....:       ||.   |.:|......|:..  .||.:
 Worm   319 NGKIEKF-----RNSTSPRNAIFGTTEY-------EFRNEVERYLYITTTFLDFE--NPVAV--- 366

  Fly   386 ILDAYDFKGDSLNN-DTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFE-----FA 444
               |..|..:.:.| |||     |:||....:......||.:..|..:     :|:||     ::
 Worm   367 ---AQHFDDELMQNMDTM-----INGDAVSIFVSAAAFSSAMANAGAD-----VYLFETRQWPYS 418

  Fly   445 GLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTGVF 509
            ...|..::|.|         :|. :.|||..:.: .|.|            .|.|:.:|.|||..
 Worm   419 FHVSDMQYFIG---------IHR-EVLHTHDMDI-LDSF------------YSKLLVNFTKTGAP 460

  Fly   510 HEESICKVSDFKEQGMCNYLHFGGNKEKYLE---DIRN 544
            ..|             .|.|.  ..|..|||   |.||
 Worm   461 SPE-------------WNSLE--PEKMNYLELRVDTRN 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	123/494 (25%)
cest-9.2	NP_741910.3	alpha/beta hydrolases	22..501	CDD:473884	136/545 (25%)