Protein Alignment Jhedup and Nlgn3

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 604
• Identity: 162/604 - (26%)
• Similarity: 250/604 - (41%)
• Gaps: 119/604 - (19%)

  Fly    28 GCMRGTL--MPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA 90
            |.:||..  :|....|..:.::|:|:|.||:|..|...|.|...|.|:.:|......|.|..:.|
Mouse    46 GKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTA 110

  Fly    91 KEWGLMGV-----------------EDCLYLNVYRP-------KNRAED---------------- 115
            ....::.|                 |||||||||.|       |.:.||
Mouse   111 VPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSG 175

  Fly   116 KLPVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQ 180
            ..|||||||||.:..|:.: |..| ..|.....|:::|:|||:|..|||||||:...||:|..||
Mouse   176 AKPVMVYIHGGSYMEGTGN-MIDG-SVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQ 238

  Fly   181 RLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILK 245
            ..||:|:.::||.|||||:::||.|...|.....|..:|.:|:||||.::..:|:. ||:..:..
Mouse   239 IQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSA-LSSWAVNY 302

  Fly   246 DPLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMP---HLTTLPVLEA 307
            .|:.....|..::.   ...|.:.|:.:.||....|:|:..       |..|   |:...||::.
Mouse   303 QPVKYTSLLADKVG---CNVLDTVDMVDCLRQKSAKELVEQ-------DIQPARYHVAFGPVIDG 357

  Fly   308 PSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPK---LRAEFN---ENFLE 366
            .    .:.:||......|..  :.:.:.|....|||..|: ...::|:   ...:|:   .||::
Mouse   358 D----VIPDDPEILMEQGEF--LNYDIMLGVNQGEGLKFV-EGVVDPEDGVSGTDFDYSVSNFVD 415

  Fly   367 HMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLK-LAEISGDFNFYYPIYETISSYVTYAN 430
            :   |...|||... :...|...|....|..|.:|..| |..:..|..:..|...|...:..|.
Mouse   416 N---LYGYPEGKDT-LRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYG- 475

  Fly   431 LEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPV--SFDDFPKD--SEDAK 491
               :|.:.|.| :....|:.|  ...:|     |.|.|:..:...:|:  ..|.||.:  ..|..
Mouse   476 ---SPTYFYAF-YHHCQSLMK--PAWSD-----AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVM 529

  Fly   492 VIQRMSSLMTDFAKTG-----------VFHEESICKVSDFKEQGMCN-------YLHFGGNKEKY 538
            :...:.:..|:|||||           ..|    .|.:.|:|.....       |||.|....
Mouse   530 LSAVVMTYWTNFAKTGDPNKPVPQDTKFIH----TKANRFEEVAWSKYNPRDQLYLHIGLKPR-- 588

  Fly   539 LEDIRNSITLTAFPIWKKL 557
               :|:....|....||.|
Mouse   589 ---VRDHYRATKVAFWKHL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	148/543 (27%)
		Aes	<106..>210	CDD:223730	50/126 (40%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	159/599 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		3/20 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832432
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740