Protein Alignment Jhedup and Cel

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_058693.2
• Gene: Cel / 24254
• RGDID: 2331
• Length: 612
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 160/589 - (27%)
• Similarity: 257/589 - (43%)
• Gaps: 104/589 - (17%)

  Fly     1 MLFAGFGVLLFVAVAVGDSLDVCLEDMGCMRG-----TLMPGYQSGEFEAFMGIPFAQPPVGPLR 60
            :||.|....|  |.|....|.....:.|.:.|     :|:.|   ...:.|.|||||....
  Rat     6 VLFLGLTCCL--AAACAAKLGAVYTEGGFVEGVNKKLSLLGG---DSVDIFKGIPFATAKT---- 61

  Fly    61 LKNPVPNEPWEGVLDAGAAKDSCIQRSYFAKEWGLMGVEDCLYLNVYRPKNRAE--DKLPVMVYI 123
            |:||..:..|:|.|.|...|..|:|.:....:  ..|.|||||||::.|:.|.:  ..|||||:|
  Rat    62 LENPQRHPGWQGTLKATDFKKRCLQATITQDD--TYGQEDCLYLNIWVPQGRKQVSHDLPVMVWI 124

  Fly   124 HGGGFFSGSAHPMASGPEYLMD------TNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRL 182
            :||.|..||.........||.|      ...|::||.|||:||.|||||||.::|||||.:||.:
  Rat   125 YGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHM 189

  Fly   183 ALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDP 247
            |:.|::::||.|||||..:|:.|.|||..|..|..:||.:|||.:.::|.:| :.||...|.::|
  Rat   190 AIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSPYNKGLIRRAISQSG-VALSPWAIQENP 253

  Fly   248 LSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMP----------HLTTL 302
            |..|:.:.|::.....::..   :|..|:...|:.|.::.       .:|          :|..:
  Rat   254 LFWAKTIAKKVGCPTEDTAK---MAGCLKITDPRALTLAY-------RLPLKSQEYPIVHYLAFI 308

  Fly   303 PVLEAPSPDAFLVEDPLDAH-RAGRINQMPWILSLSSRAGEGSLFIMRAFIN----PKLRAEFNE 362
            ||::..    |:.:||::.: .|..|:.:..|..:     :|.||   |.::    .|.:.:..|
  Rat   309 PVVDGD----FIPDDPINLYDNAADIDYLAGINDM-----DGHLF---ATVDVPAIDKAKQDVTE 361

  Fly   363 NFLEHMALLLNLPEGTPVQMVSEILDAY--DFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSY 425
            .....:.....:.:|  ::......|.|  .:..|....:....:.....|..|..|....::.:
  Rat   362 EDFYRLVSGHTVAKG--LKGTQATFDIYTESWAQDPSQENMKKTVVAFETDILFLIPTEMALAQH 424

  Fly   426 VTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDA 490
            ..:|...:.  :.|:|.......|...:        :||.|.||..:....|.: ......::|.
  Rat   425 RAHAKSAKT--YSYLFSHPSRMPIYPKW--------MGADHADDLQYVFGKPFA-TPLGYRAQDR 478

  Fly   491 KVIQRMSSLMTDFAKTGVFHEESICKVSDFKEQGMCN---------YLHFGGNKEKYLEDIRNSI 546
            .|.:.|.:..|:|||:|              :..|.|         |....||   || ||...|
  Rat   479 TVSKAMIAYWTNFAKSG--------------DPNMGNSPVPTHWYPYTTENGN---YL-DINKKI 525

  Fly   547 TLTA 550
            |.|:
  Rat   526 TSTS 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	139/506 (27%)
		Aes	<106..>210	CDD:223730	51/111 (46%)
Cel	NP_058693.2	COesterase	26..542	CDD:278561	153/567 (27%)
		Aes	<118..>247	CDD:223730	61/129 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..612
		4 X 11 AA tandem repeats, O-glycosylated region	556..599

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336381
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740