Protein Alignment Jhedup and Ces2b

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 567
• Identity: 173/567 - (30%)
• Similarity: 250/567 - (44%)
• Gaps: 117/567 - (20%)

  Fly     6 FGVLLFVAVAVG----DSLDVCLEDMGCMRGTL--MPGYQSGEFEAFMGIPFAQPPVGPLRLKNP 64
            ||:||.:....|    ::..:.....|.:||:|  :...::| ...|:|||||:|||||||...|
Mouse    15 FGLLLLLGHVQGQDSPEASPIRNTHTGQVRGSLVHVKDTKAG-VHTFLGIPFAKPPVGPLRFAPP 78

  Fly    65 VPNEPWEGVLDAGAAKDSCIQRSYFAKEWGL-----MGVEDCLYLNVYRPKNRAE-DKLPVMVYI 123
            ...|||.||.|..|....|:|.....||..|     ...|||||||:|.|.:..| ..|||||:|
Mouse    79 EAPEPWSGVRDGTAHPAMCLQNLGVMKEIKLKLPPVSTSEDCLYLNIYTPAHAHEGSNLPVMVWI 143

  Fly   124 HGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQ 188
            ||||..:|.| .|..| ..|.....:|:||:.||||..||.||||:|..||:||.||..||:|||
Mouse   144 HGGGLVAGMA-SMYDG-SLLAAIEDLVVVTIQYRLGVLGFFSTGDQHARGNWGFLDQVAALRWIQ 206

  Fly   189 KHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMS----------LTGTMFLSAMKI 243
            ::||.|||.|.:||:.|.||||.|...|::||.|||||..::.          :|.|..:.:..:
Mouse   207 QNIAHFGGKPDRVTIFGESAGGTSVSSHVVSPMSKGLFHGAIMESGVALLPYLITDTSEMVSTTV 271

  Fly   244 LKDPLSQARRLGKELAI------DQAESLSSQDLAEALRNVC--------PKKLLVSVDSLKVWD 294
            .|  ||....:..|..:      .:||.|:...|.:.:..|.        ||:||.|.|.
Mouse   272 AK--LSGCEAMDSEALVRCLRGKSEAEILAINKLVQMIPAVVDGEFFPRHPKELLASEDF----- 329

  Fly   295 NMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAE 359
               |         |.|....|.:          ::..|.:.:..    ||...::......|:|.
Mouse   330 ---H---------PVPSIIGVNN----------DEFGWTIPVVM----GSAQTIKEITRENLQAV 368

  Fly   360 FNENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTM-LKLAEISGDFNFYYPIYETIS 423
            ....    .|.|:..||.:.:.|       .::.||:.:..|: ::..|:..||.|..|..:.
Mouse   369 LKNT----TAQLMLPPECSDLLM-------EEYMGDTEDAQTLQIQFTEMMEDFMFVIPALQV-- 420

  Fly   424 SYVTYANLEENPLFIYIFEF----AGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFP 484
                 |..:.:...:|.:||    |.|..:....        :.|.|.|:      ||..|..|.
Mouse   421 -----AYFQRSHASVYFYEFQHQIASLKDVRPTH--------VKADHADE------IPFVFGYFF 466

  Fly   485 KD-----SEDAKVI-QRMSSLMTDFAKTGVFHEESI--CKVSDFKEQ 523
            .|     :|..|:: :||.....:||:.|..:.|.:  ..|.|..||
Mouse   467 WDMKLDFTEGEKLLSRRMMKYWANFARHGNPNSEGLPYWPVMDHDEQ 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	161/519 (31%)
Ces2b	NP_937814.1	COesterase	32..535	CDD:395084	168/550 (31%)