Protein Alignment Jhedup and cest-28

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 152/584 - (26%)
• Similarity: 235/584 - (40%)
• Gaps: 142/584 - (24%)

  Fly    28 GCMRGTLMPGYQSGE--FEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA 90
            |.::|.:   |:.|:  .:.::|||||:|.|   |.|.|.|...||.|.|.......|.|...||
 Worm    22 GPIQGNV---YRIGDKTVDGYLGIPFAKPLV---RFKKPEPAGTWEEVRDCTKYGPRCPQSGPFA 80

  Fly    91 KEWGLMGVE-----DCLYLNVYR----PKNRAEDKLPVMVYIHGGGFFSGSAHP----MASGPEY 142
            :.......:     :||.|||:.    .||..:.: ||||||||||:...::..    ..:|...
 Worm    81 EAINFQKDDIPDEANCLTLNVFSKISDSKNFNKTR-PVMVYIHGGGYECSASRDYCDYSVAGTLP 144

  Fly   143 LMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHS 207
            |.|   ||:||:|||:|..||.:|||...||||...|..|.|.||||||.:|||||..:|:.|.|
 Worm   145 LKD---VVVVTLNYRVGILGFFTTGDTVCPGNFALWDLTLGLNWIQKHIESFGGDPGNITIFGQS 206

  Fly   208 AGGISAHLHMISPNSKGLFQNSMSLTGTMFLS-AMKILKDPLSQARRLGKELAIDQAESLSSQDL 271
            ||.....|..:||:|:.||...:.::|..... |::.............:.|..|...|
 Worm   207 AGAACVDLLALSPHSRDLFNRVIVMSGGALCEYAVRTANSQAKVCYEFARHLGYDGTNS------ 265

  Fly   272 AEALRNVCPKKLLVSVDSLK----------VW------DNMPHLTTLPVLEAPSPD--------- 311
             :.|.|....|.|..::.:.          .|      |..|.......:.||..|
 Worm   266 -QTLFNWMKSKPLEEIEKMNGFQVPASGILAWTPNLDDDFFPKSLDELRIGAPKKDIMMGFAEHE 329

  Fly   312 ----AFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLL 372
                .||::||.....|                       ::.::|...:.:..::|
 Worm   330 GLFFEFLIKDPTPPLEA-----------------------LKLYVNEYYKKDTGDHF-------- 363

  Fly   373 NLPEGTPVQMVSEILDAYDFK-GDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPL 436
               |.|.    ::|::.|... .|:....|..:|.:..||..|...:::...:.:.:.    |.:
 Worm   364 ---EATR----NKIIEFYSRNVEDTDEKSTKERLIDFVGDALFTAGVFDNAKNCLKHG----NNV 417

  Fly   437 FIYIFE------FAGLNSITKFFAGT--TD-DYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKV 492
            ::|||:      |........|.|.|  || .|.||     :||        :.||....|:.|:
 Worm   418 WLYIFDYCNPSGFGNQEEFMTFVAPTHCTDLRYVLG-----EGL--------YSDFQPTEEEHKM 469

  Fly   493 IQRMSSLMTDFAKTGVFHEESICKVSDFKEQG-------------MCNYLHFGGNKEKYLEDIR 543
            |::|:::.::|||.|..:|....:...|....             |.|..|  .::.|:||.||
 Worm   470 IEKMTTIYSNFAKYGNPNEHGSSEWEKFTLDNPRRHFQISYPRGKMRNDYH--PDRMKFLELIR 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	140/531 (26%)
cest-28	NP_504691.2	COesterase	17..526	CDD:395084	147/577 (25%)