Protein Alignment Jhedup and cest-30

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 170/619 - (27%)
• Similarity: 248/619 - (40%)
• Gaps: 134/619 - (21%)

  Fly     5 GFGVLLFVAVAVGDSLDVCLE--------DMGCMRGTLMPGYQSGE--FEAFMGIPFAQPPVGPL 59
            |.|.||...|..|..:::..|        ..|.:||.:.. :::|.  .:.::|||||:.|||.|
 Worm     8 GIGCLLLSIVEGGFLVNLTPEKNSQILNAPCGPIRGNIYK-HKNGTKIVDGYLGIPFAKAPVGAL 71

  Fly    60 RLKNPVPNEPWEGVLDAGAAKDSCIQRSYF----AKEWGLMGVEDCLYLNVYRPKNRAED---KL 117
            :.|.||..|.|....|.......|.|...|    ||.......|:||.|||:.|:.:..:   .|
 Worm    72 KFKKPVAAEKWTEPRDCYEYGPGCPQTGRFAALTAKSTAAFAEENCLTLNVFAPRWKLAEFPKGL 136

  Fly   118 PVMVYIHGGGFFSGSAHPM----ASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFK 178
            ||:|||:|||:..|....|    .:|...|.|   |::|||||||||.|||:..|....||:|..
 Worm   137 PVLVYIYGGGYEIGFTSYMDDYSLTGTLPLKD---VIVVTMNYRLGPLGFLTIADGIANGNYGLW 198

  Fly   179 DQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKI 243
            ||.|||||:|.:||:|||:|:.||:.|.|||..|.....:||:|..|||.|:|::||.|.:....
 Worm   199 DQTLALQWVQDNIASFGGNPESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTAFCNFAIR 263

  Fly   244 LKDPLSQARRLG--KELAIDQA-ESLSSQDLAE--ALRNVCPKKLLVSVDSLKV----------W 293
            .||.     .:|  ||.|..|. ....||.|.:  ..:||...|.:....|...          .
 Worm   264 PKDV-----EVGVCKEFAQFQGYTGTDSQSLFDWYMAQNVSKFKEVAGFQSTAAGAVPFIPNFDG 323

  Fly   294 DNMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRA 358
            |..|....:...|||..||.:.                 ::::.|        :.....||....
 Worm   324 DFFPKPFDILRREAPKKDALIT-----------------VVTMES--------VGMIIFNPLFAN 363

  Fly   359 EFNENFLEHMALLLNLPEGTPVQMVSEIL--DAYDFKGDSLNNDTMLKLAEIS------------ 409
            .:| ||           ||    .::|..  |..|:..|.....|...|.:::
 Worm   364 AYN-NF-----------EG----FINETYGPDVTDYYADVKKKLTGFYLKDVNASDKATVNRRVV 412

  Fly   410 ---GDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGL 471
               .|..|.....:.:.|||.|.|.      :|:..|...|..||........: ..|.|..|..
 Worm   413 DYVSDSVFNSGTLDAVKSYVKYGNK------VYLGSFNYFNDATKDMVELMQPF-KEASHSSDFK 470

  Fly   472 HTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTGVFHEES----------------------I 514
            :.....|..:..|.| |:.:|:....:||.:|.|.|..:.:|                      .
 Worm   471 YYFGSGVMANFTPTD-EEMEVMDMSGTLMANFVKYGDPNGKSGTKPWKPYTILKPNMYYKIDYPT 534

  Fly   515 CKVSDFKEQGMCN-YLHFGGNKEKYLEDIRNSIT 547
            |::||..:.|... |.....|.:||.:.:...::
 Worm   535 CEMSDNFQNGRLRIYDDINKNSKKYQQIVYGKVS 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	152/521 (29%)
		Aes	<106..>210	CDD:223730	52/110 (47%)
cest-30	NP_504407.1	COesterase	31..539	CDD:278561	156/565 (28%)
		Aes	<122..>230	CDD:223730	52/110 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157218
Domainoid	1	1.000	183	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.800