Protein Alignment Jhedup and cest-3

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 142/601 - (23%)
• Similarity: 219/601 - (36%)
• Gaps: 165/601 - (27%)

  Fly     9 LLFVAVAVGDSLDVCLEDMGCMRGTLMPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGV 73
            :|||....|....:.....|.:.|..:    :.:...|..:|||:||:|.||...|....||:.:
 Worm    10 ILFVFTLNGSGQRIISTTYGKLEGKTV----NVDQHMFKNVPFAKPPLGKLRFSLPEWTNPWKNI 70

  Fly    74 LDAGAAKDSCIQRSYFAKEWGLMGV-EDCLYLNVYRPKNRAEDK-LPVMVYIHGGGFFSGSAHPM 136
            .:|.....||...|....:.....: ||||||||:..:...:.| ...:||.||||....||  :
 Worm    71 RNATEYSPSCFSNSSMRTDSNFFPMSEDCLYLNVFTNEYCLKSKNCSTVVYYHGGGINMDSA--V 133

  Fly   137 ASGPEYLMD---TNKVVMVTMNYRLGPFGFLSTGDEHM-PGNFGFKDQRLALQWIQKHIATFGGD 197
            .....::::   ...||.:...||||.||.|..|..:: |.|....|..|||::|.:.|:.|||.
 Worm   134 QFNDTFILERYVKENVVFIIPAYRLGIFGLLYFGSNNLVPQNLAIHDCELALRFIHQEISNFGGH 198

  Fly   198 PKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQ 262
            ...:.::|||||   ||:.:|...|:.:..:...:...:.||.:.....|         ||.|.
 Worm   199 KDDINLMGHSAG---AHISLIFGFSRHIDPDHKLINRIIVLSPVPSYDMP---------ELLIK- 250

  Fly   263 AESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRI 327
                :..|.||  |..|.|:.:.:.|:
 Worm   251 ----NCYDFAE--RVGCYKRNVTARDT-------------------------------------- 271

  Fly   328 NQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEGTPVQMVSE-ILD--A 389
               ..:..|..:...|.:.:.|...|.:|   :..|||          .|.|.....| |.|  .
 Worm   272 ---EIVKCLRKKDARGLMSMQRLMENDRL---YFWNFL----------AGEPFMYRDESIADFKE 320

  Fly   390 YDFKGDSLNNDTMLKLA----------------------EISGDFNFYY---PIYETISSY---- 425
            |..|.|.|..:|:.::.                      |::..||||:   |:..|..|:
 Worm   321 YAVKRDMLIGNTVDEVKWKRLKKENPAIAGSFMDWENPYEVAHKFNFYHDSAPVNSTYESFTQGI 385

  Fly   426 ----VTYANLEENP-LFIYIFEF----AGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFD 481
                .|||..:.|. ..:|:|:.    :...|..::|.||         |.:| .||..:.: .|
 Worm   386 FVSTATYAEAQANAGGTVYLFQSNQQPSSHVSDMQYFVGT---------HRED-YHTSDMDI-MD 439

  Fly   482 DFPKDSEDAKVIQRMSSLMTDFAKTGVFHEESICKVSDFKEQGMCNYLHFGGNKEKYL-----ED 541
            .|            .|.::.:|.|.|     |...|.:.......||.....|.||.:     ||
 Worm   440 TF------------YSKMIVNFTKFG-----SPSPVWEPLVPSRMNYYALEVNTEKGIWPRMEED 487

  Fly   542 IRNS------ITLTAF 551
            ...|      |.:|||
 Worm   488 FHESDVNFWFINMTAF 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	122/523 (23%)
		Aes	<106..>210	CDD:223730	35/108 (32%)
cest-3	NP_510042.2	Abhydrolase	23..496	CDD:304388	134/579 (23%)
		Aes	<118..>254	CDD:223730	44/154 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157109
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740