Protein Alignment Jhedup and glit-1

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 527
• Identity: 143/527 - (27%)
• Similarity: 241/527 - (45%)
• Gaps: 135/527 - (25%)

  Fly    46 FMGIPFAQPPVGPLRLKNPVPNEPWEGV-------LDAGAAKDSCIQRS---YFAKEWGLMGVED 100
            |:|:|:|:||....|.|.|.....:.|.       ..|..|:|  :::|   :....:..|..||
 Worm   109 FLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQD--VEKSPSPFVDHPYPFMVDED 171

  Fly   101 CLYLNVYRP---KNRAEDKLPVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFG 162
            |||||::.|   || |:...||:|:.|||.|.:|||:   ..|.:.:.:..:|:||:|||||.||
 Worm   172 CLYLNIFSPDISKN-AQTTYPVIVFFHGGNFQTGSAN---EWPAHGLASRGMVVVTVNYRLGAFG 232

  Fly   163 FLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQ 227
            |:|.||.. .||:|.:||||||::::.:|.||||||:.|||:||.||..|...||.||.|:.||:
 Worm   233 FMSMGDSE-TGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHLFR 296

  Fly   228 NSMSLTGTMFLSAMKILKDPL--SQARRLGKELAIDQAE---------SLSSQDLAEALRNVCPK 281
            ::.:::|........|.|..|  :...:||:.....||.         :.|:.|:.:|.||: |.
 Worm   297 SAATMSGAEVSYHSYIGKTALAFNNTMKLGRYAGCTQAVAQHRWDCILTRSTGDIIDATRNI-PI 360

  Fly   282 K-----LLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAG 341
            :     .:.:||. |.....| |.||  :.|||.:..:            ::.:|.::.::::.|
 Worm   361 EYNRYLFMPTVDG-KYLPGNP-LWTL--VNAPSGETSI------------MSPVPMLIGMNAQDG 409

  Fly   342 EGSLFIMRAFINPKLRAEFNE-NFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKL 405
            .      ...:..:...||:: |.::|                 |.|.:|..:....:|.:|.:
 Worm   410 S------EVVLEDRRLGEFSQFNDVDH-----------------EYLKSYSLEYCYRHNYSMNR- 450

  Fly   406 AEISGDFNFYYPIYETISSYVTYAN------LEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGA 464
             |.:.|        ..:|.|..:.:      ::||  ||   :||            ||.|....
 Worm   451 -EATAD--------AILSKYTFWPDRAAAWAIKEN--FI---QFA------------TDAYYTAP 489

  Fly   465 VHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTGVFHEESICKVSDFKEQGMCN-- 527
            :.:...||:             |..::|.|.:::.  :|::    ...::..:.|:  .|:|.
 Worm   490 MQLSSHLHS-------------SSGSRVFQYVNNY--NFSR----QHPNLLFIPDW--MGVCRDC 533

  Fly   528 --YLHFG 532
              ||.||
 Worm   534 DLYLMFG 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	136/497 (27%)
glit-1	NP_508807.1	alpha/beta hydrolases	98..629	CDD:473884	143/527 (27%)