Protein Alignment Jhedup and cest-2.2

DIOPT Version :9

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001256567.1
• Gene: cest-2.2 / 179917
• WormBaseID: WBGene00013874
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 144/553 - (26%)
• Similarity: 228/553 - (41%)
• Gaps: 116/553 - (20%)

  Fly    37 GYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCI--QRSYFAKEWGLMGVE 99
            |.|:|  ..|.|:|:.:||||.||.:.|.|.:||:|||:|...|.:|:  |:..:....|....|
 Worm    42 GNQTG--IVFFGVPYVEPPVGNLRFRKPRPPKPWDGVLEAKEYKAACMSDQKKTYKNGVGGPVSE 104

  Fly   100 DCLYLNVYRPKNRAEDK-LPVMVYIHGGGFFSGSAHPMASGPEYLMDT-----NKVVMVTMNYRL 158
            ||||.||:..:...|.| ..||:.||||.|...||  .|..||.:::.     ..:|:||.||||
 Worm   105 DCLYANVFTNQYCLEHKNCSVMLTIHGGRFVIESA--SAYDPEIIINNFVGQGRNIVVVTFNYRL 167

  Fly   159 GPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSK 223
            |.||......::...|||..|....::|.:|.|..||||..::|:.|||||.:.......||.||
 Worm   168 GLFGLGMLNGDNQDTNFGLYDILEVVRWTRKEIKNFGGDKDRITMQGHSAGAVFTAAFSTSPLSK 232

  Fly   224 GLFQNSMSLTGTMF-LSAMKILKDPLSQARRLG-----------KELAIDQA----ESLSSQDLA 272
            ||....:.::.:|. ||....:|:....||.:|           ..:.:::|    .|.|:|.:.
 Worm   233 GLIHQQIIMSASMSNLSKKSNVKELTVVARIVGCLPDEHGFPKLSNVEVEKAYTCLRSKSAQQIL 297

  Fly   273 EA----LRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWI 333
            :|    |||                      ||..:.:......:.|:.|.:.:....|..:..:
 Worm   298 DAQLYMLRN----------------------TTYYIGQGHIDGIYQVDYPDNLYATNSIYPINTM 340

  Fly   334 LSLSSRAGEGSLFIMRAFINPKLRAE---FNENFLEHMAL-LLNLPEGTPVQMVSEILDAYDFKG 394
            :..::    ..|...|..::||...:   ..:|..||:.. |...||....:..:...:..|.|
 Worm   341 IGTTT----AELMDSRYIVDPKNTGKKEILLQNLCEHIGYELYKEPEEFSQKCRNFYKNGEDAK- 400

  Fly   395 DSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANL---EENPLFIYIFEF--AGLNSITKFFA 454
                        .:..|..|||       ..:..||:   ::..:|:|.|::  || |:..|:
 Worm   401 ------------SLGDDMEFYY-------GAIQLANVHSSKDTNVFVYSFDYKEAG-NAYKKY-- 443

  Fly   455 GTTDDYGLGAVHMDD---GLHTIRIPVSFDDFPKDSEDAKVIQRM-SSLMTDFAKTGVFHEESIC 515
                |..|...|.:|   ...|.|...|..|:        ||:.: |.:..||...|
 Worm   444 ----DKSLSPKHGEDFAYAFGTNRGNFSTKDY--------VIEYIYSGMFADFVNFG-------- 488

  Fly   516 KVSDFKEQGMCNYLHFGGNKEKYLEDIRNSITL 548
            ..|..::|....|.  ...:|.:|.|...:.|:
 Worm   489 DPSPLEDQEWAQYT--PEKREYFLIDFDKNFTM 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	COesterase	31..508	CDD:278561	136/511 (27%)
		Aes	<106..>210	CDD:223730	41/109 (38%)
cest-2.2	NP_001256567.1	Abhydrolase	25..534	CDD:389770	144/553 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157004
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940