Protein Alignment Jhedup and cest-1.1

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 150/608 - (24%)
• Similarity: 251/608 - (41%)
• Gaps: 132/608 - (21%)

  Fly     8 VLLFVAVAV------------GDSLDVCLEDMGCMRGTLMPGYQSGEFEAFMGIPFAQPPVGPLR 60
            |||.:.:.|            |..|::....:|....|:           |:||||.:||:|.||
 Worm     7 VLLLIQMYVCKRVQLSSGTIEGKILNISYSPLGNQSATV-----------FLGIPFVEPPIGDLR 60

  Fly    61 LKNPVPNEPWEGVLDAGAAKDSCIQ---RSYFAKEWGLMGVEDCLYLNVYRPKNRAEDK-LPVMV 121
            .:.|.|.:.|||||.....|.:|:.   ::|..|..|.:. ||||||||...:...|:| ..||:
 Worm    61 YRKPRPPKSWEGVLVTNEYKSACMSNATKTYKNKFGGPIS-EDCLYLNVLTNEYCLENKNCSVMM 124

  Fly   122 YIHGGGFFSGSAHPMASGPEYLMDT-----NKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQR 181
            .:||||:.:.||...  .||.|::.     ..:|:||.|||||.|.|.....:....|||..|..
 Worm   125 IVHGGGYLTESASTF--NPEILINNFVGQGRNIVVVTFNYRLGLFSFGQFNGDRGDKNFGLYDMI 187

  Fly   182 LALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMF-LSAMKILK 245
            .::.|:::.|..|||:..::|:.|||||.........||.:|||....:.::..|. :|.....|
 Worm   188 ESVNWVRREIENFGGNKNRITLAGHSAGASMIVAFTSSPLTKGLVHQQIIMSAPMTNMSKKSNFK 252

  Fly   246 DPLSQARRLG---KELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVW--DNMPHLTTLPVL 305
            .....|:.:|   :|:..::......::....||    ||....:...::|  .|..:....|
 Worm   253 GMTVMAQMVGCLSEEIGFNKLSEEQVENTYSCLR----KKSAQQILDAQLWLLQNSTYFLGAP-- 311

  Fly   306 EAPSPDAFLVEDPLDAHRAGRINQMPWILSLSS-RAGEGSLFIMRAFINPKLRAEFNENFLEHMA 369
              |..:.||.:.|.:.:.:..|..:..::..:: ...|.|..|..||.:.|:  |..||..:|:.
 Worm   312 --PIDEHFLTDYPENLYASKSIYPINTLIGTTTLEVEESSYIIDPAFADKKV--ELLENLCDHIG 372

  Fly   370 -LLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEE 433
             :|...||....:...:.::     |:|..|        :|.:..||.|..:...|: |..|.:
 Worm   373 YVLYEEPETFSKKCQKQYMN-----GNSSMN--------LSNEMEFYTPAIDFADSH-TSGNTK- 422

  Fly   434 NPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDF------------PKD 486
              :|:|.:::.|        ||...|..|          .:|.|...:|.            |||
 Worm   423 --VFLYSYDYRG--------AGPAYDRYL----------EVRSPHHSEDLIYVFGTHRGIFAPKD 467

  Fly   487 SEDAKVIQRM-SSLMTDFA-----------KTGVFHEESICKVSDFKEQGMCNYLHFGGNKEKYL 539
                .:|::: |.:..||.           |...:.:|:       :|..:.|:     :|....
 Worm   468 ----YIIEKIYSGMFADFVNFENPLPSGDQKWNQYTKEN-------REHFLINF-----DKNFIT 516

  Fly   540 EDIRNSITLTAFPIW----KKLF 558
            ..:|::....|:..|    ||.|
 Worm   517 PGMRDNYYTEAYEFWSTVGKKSF 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	133/517 (26%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:395084	142/586 (24%)