Protein Alignment Jhedup and cest-34

DIOPT Version :10

• Sequence 1: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 159/586 - (27%)
• Similarity: 247/586 - (42%)
• Gaps: 142/586 - (24%)

  Fly    28 GCMRGTLMPGYQSG--EFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFA 90
            |.:.|.|   |:.|  |...::|:|:|:||.|.:|...|||.:.|....|.......|....
 Worm    22 GPVLGNL---YRHGDKEVHGYLGMPYAKPPTGEMRFAKPVPADDWTETRDCTKYGPRCPPSG--- 80

  Fly    91 KEWGLMGVEDCLYLNVYRP----------------KNRAEDKLPVMVYIHGGGFFSGSAHPMASG 139
                 .|:|..:::|...|                .:..::..|||||:|||||...|:....
 Worm    81 -----QGLEKGMFVNPDEPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEISSSREFC-- 138

  Fly   140 PEYLMDT----NKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKK 200
             :|.:.:    ..|::||||||||..||.:||||..|||||..||.|||||:|||||:|||||..
 Worm   139 -DYSISSTLPMKDVILVTMNYRLGILGFFTTGDEVCPGNFGLWDQTLALQWVQKHIASFGGDPNN 202

  Fly   201 VTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGT-MFLSAMK-------ILKDPLSQARRLGKE 257
            ||:.|.||||....|..:||:|:.|||..:.::|: |...||:       :..|.|:   |||
 Worm   203 VTLFGQSAGGACVDLLTLSPHSRDLFQKVVPMSGSAMCEFAMRTAENEAHVFDDILA---RLG-- 262

  Fly   258 LAIDQAESLSSQDLAEALRNV-CPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDA 321
                 .....|::..|.:|:: |.|   ::..:...:.....::.     .|:.|......|||.
 Worm   263 -----FTGSGSKERLEFMRSLPCDK---ITGKTGYTYKQSGFMSL-----CPNYDGDFFPKPLDE 314

  Fly   322 HRAGRINQMPWILSLSSRAGEGSLFIMRAF------------INPKLRAEFNENFLEHMALLLNL 374
            .|.....:   ||.......||.||   ||            :..|:..::.|:.::.:
 Worm   315 LRKDASKR---ILMTGIVGNEGLLF---AFDRNTPYKDYTDLLRLKIEEDYKEDVVDDV------ 367

  Fly   375 PEGTPVQMVSEILDAYD---FKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPL 436
             ||    :..||.:.|.   .:||  ....|.|.||..||..|:..:..|..:...:.    :.:
 Worm   368 -EG----IRKEIFEYYTKNISEGD--EEAIMRKAAEFVGDSIFHTGVRATAQNAAEHG----DEV 421

  Fly   437 FIYIFE------FAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDD-----FPKDSEDA 490
            ::|.|:      ||.|.....:...|               |.:.:...|.|     |....|:.
 Worm   422 WLYNFDYCNPDGFAPLKGYLPYIEPT---------------HGMELRYLFGDGIISKFEPTEEEL 471

  Fly   491 KVIQRMSSLMTDFAKTGVFHE--ESICKVSD-----------FKEQGMCNYLHFGGNKEKYLEDI 542
            |::.:.:::..:|||.|..:|  .|..:..|           :...||.:  .|.|.:.|:||:|
 Worm   472 KMLDKFTTMFANFAKYGNPNETGSSAWEKFDPARPGRHYRISYPNSGMED--EFSGGRWKFLEEI 534

  Fly   543 R 543
            |
 Worm   535 R 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	145/533 (27%)
cest-34	NP_001360105.1	COesterase	15..517	CDD:395084	150/564 (27%)